Mehmet UÇUCU, Fatma ALİBAZ ÖNER, Selen YURDAKUL, Mecdi ERGÜNEY

BOZULMUŞ AÇLIK GLUKOZU OLAN AKUT KORONER SENDROMLU HASTALARDA HASTANE İÇİ MORTALİTE

Giriş: Diyabet artık koroner arter hastalığının eşdeğeri sayılmaktadır.Ayrıca hem bozulmuş açlık glukozu(IFG) hemde bozulmuş karbonhidrat toleransı (IGT) kardiyovasküler hastalık için birer risk faktörüdür.Bu çalışmada akut koroner sendrom (AKS) tanısı alan; diyabetli ve IFG li hastalar arasında hastane içi mortalitenin karşılaştırılması amaçlanmıştır. Yöntem: Çalışmaya akut AKS tanısı alan 65 yaş altı hastalar alındı ,ilk 7 gündeki mortaliteleri değerlendirildi.Hastalar açlık kan şekerine göre diyabeti olan, diyabeti olmayan ve bozulmuş açlık glukozu olanlar olmak üzere üç gruba ayrıldı. Bulgular: Toplam 375 hasta çalışmaya dahil edildi. Tüm hastalarda hospitalizasyon dönemindeki mortalite; diyabeti olan hastalarda % 6.7, diyabeti olmayanlarda % 2.6, bozulmuş açlık glukozu olanlarda %7.0 olarak bulundu.AKS sonrası erken dönemde mortalite IFG ve diyabetli hastalarda yaklaşık aynı oranda tespit edildi. Bu oran normal kan şekeri olanlardan anlamlı derecede yüksek tespit edildi. Sonuç: Dolayısıyla IFG; diyabet gibi koroner kalp hastalığı için risk faktörüdür ve mortalite üzerinde onun kadar etkilidir.Sonuç olarak,açlık plazma glukozu,kardiyovasküler hastalık riskinin belirlenmesinde ve koroner arter hastalık riskini azaltıcı yaklaşımların belirlenmesinde son derece faydalıdır.Anahtar Kelimeler: Akut koroner sendrom, Bozulmuş açlık glikozu, Diyabet, Mortalite

Anahtar Kelimeler:

Akut koroner sendrom, Bozulmuş açlık glikozu, Diyabet, Mortalite

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Objectives: Diabetes mellitus is considered to be equivalent to coronary artery disease(CHD). Both impaired fasting glucose(IFG) and impaired glucose tolerance (IGT) are risk factors for cardiovascular disease. We aimed to compare the mortality during hospitalization between IFG and diabetes in patients with acute coronary syndrome (ACS). Methods: The patients under 65 years of age, who had been diagnosed as ACS; were evaluated for mortality during the first 7 days. The patients were divided into three groups as the first group diabetic, the second group non-diabetic patients , the patients with IFG. Results: A total of 375 patients were enrolled. The mortality rate was found to be 6.7% in patients with diabetes, 2.6% in patients without diabetes , 7.0% in patients with an IFG. The mortality rate of the patients with IFG and the patients with diabetes were approximately the same and this rate was significantly higher than in those with normal blood glucose during the acute phase of ACS. Conclusion: The IFG affects mortality as much as diabetes. Fasting plasma glucose is beneficial, in determining the cardiovascular risks and in the modification of the therapy to reduce the risk of CHD

Keywords:

Acute coronary syndrome, Impaired fasting glucose, Diabetes, Mortality,

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