Kıymet K BİNNETOĞLU, Elif KARAKOÇ AYDINER, Safa BARIŞ, Ahmet ÖZEN, Ayşe İrem ZÖHRE, Feyyaz BALTACIOĞLU, RAFİ HANER DİRESKENELİ, Işıl BARLAN

Bir ergende Takayasu arteritinin atipik presentasyonu

Takayasu arteriti çocuklarda nadir görülen bir hastalıktır. Klinik bulgular özgün değildir ve tanısal bir laboratuvar test mevcut değildir. Burada, atipik bir klinikle başvuran bir ergende Takayasu arteriti sunulmaktadır. Onbeş yaşında kız çocuk kliniğimize 2 aydır süren kilo kaybı, ateş, halsizlik ve sırt ağrısı ile başvurdu. Fizik muayenede büyüme gelişmesi normal olan hastada patolojik bulguya rastlanmadı. Laboratuvar testlerinde akut faz reaktanları yüksek bulundu. Manyetik resonans ile anjiografik görüntülemelerde aorta duvarında düzensizlik ve daralmalar saptandı. Sonuç olarak, çocuklarda Takayasu arteritinde nonspesifik bulgular görülmektedir. Laboratuvar testleri tanısal olmamakla beraber radyolojik bulgular oldukça özgündür. Tedavide sistemik steroidler ve immusupresanlar kullanılmakta ancak çocuklarda seyir erişkinlerden daha ağır olmaktadır

Anahtar Kelimeler:

Ergen, HLAB51, Takayasu arteriti, Vaskülit

Atypical presentation of Takayasu’s arteritis in an adolescent

Takayasu`s arteritis is rarely seen in childhood. In addition, symptoms are nonspecific and diagnostic laboratory marker is unavailable. We hereby described an adolescent with an atypical presentation of Takayasu`s arteritis. A 15-year-old girl was admitted to our clinic with the symptoms of weight loss, fever, back pain, and malaise since 2 months. Physical examination ended with normal vital signs, centiles and no other pathological findings. Laboratory findings showed increased acute phase reactants. Irregularities in the aortic wall and luminal narrowing of aorta were detected in magnetic resonance angiography. In conclusion, children with Takayasu`s arteritis present with nonspecific symptoms. No laboratory test is diagnostic, whereas abnormalities in large vessels in radiology are specific for the disease. Mainstay of treatment is systemic steroids and immunosuppressants and outcome is worse in children than in adults.

Keywords:

Adolescent, HLAB51, Takayasu`s arteritis, Vasculitis,

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