CT-guided lung biopsy: diagnostic accuracy and complication rates of biopsy techniques
Objective: We aimed to evaluate the diagnostic accuracy and complication rates of computed tomography (CT)-guided core needle biopsy and fine needle aspiration biopsy (FNAB). Materials and Methods: Patients who underwent CT-guided lung mass biopsy were included. The patients were evaluated in terms of age, gender, lesion diameter, lesion localization, depth of the mass, type of biopsy procedure (core needle biopsies and FNAB). Results: The accuracy rate of FNAB in diagnostic material was found to be 100% in terms of benign, malignant and all lesions. The specificity and sensitivity of FNAB was found to be 100%. The diagnostic accuracy rate of core needle biopsy was found to be 70% in benign lesions, 100% in malignant lesions. The specificity of core needle biopsy was 90% and sensitivity 100%. There was no statistically significant difference between the two biopsy techniques in terms of complications. Conclusion: In conclusion, we found that the diagnostic rates of FNAB and core needle biopsy were close in malignant lesions, the diagnostic rate of core needle biopsy was higher in benign lesions, and there was no difference in terms of complications in both biopsy techniques.
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- [1] Richardson CM, Pointon KS, Manhire AR, Macfarlane JT.
Percutaneous lung biopsies: a survey of UK practice based
on 5444 biopsies. Br J Radiol 2002;75: 731-5. doi:10.1259/
bjr.75.897.750731
- [2] Brioulet J, David A, Sagan C, Cellerin L, Frampas E, Morla
O. Percutaneous CT-guided lung biopsy for the diagnosis of
persistent pulmonary consolidation. Diagn Interv Imaging
2020;101:727-32, doi:10.1016/j.diii.2020.07.007
- [3] Yeow KM, See LC, Lui KW, et al. Risk factors for pneumothorax
and bleeding after CT-guided percutaneous coaxial cutting
needle biopsy of lung lesions. J Vasc Intervent Radiol 2001; 12:
1305-12. doi: 10.1016/s1051-0443(07)61556-5
- [4] Çakır Ö, Çam İ, Koç U, Çiftçi E. Evaluation of major
complications associated with percutaneous CT-guided
biopsy of lung nodules below 3 cm. Turk J Med Sci 2020;50:
369-74. doi:10.3906/sag-1908-73
- [5] Manhire A, Chairman CM, Clelland C, et al. Guidelines for
radiologically guided lung biopsy. Thorax 2003;58:920-36.
doi: 10.1136/thorax.58.11.920
- [6] Layfield LJ, Coogan A, Johnston WW, et al Transthoracic fine
needle aspiration biopsy: sensitivity in relation to guidance
technique and lesion size and location. Acta Cytol 1996; 40:
687-90. doi: 10.1159/000333940.
- [7] Larscheid RC, Thorpe PE, Scott WJ. Percutaneous
transthoracic needle aspiration biopsy: a comprehensive
review of its currentrole in the diagnosis and treatment of lung
tumors. Chest 1998; 114:704-09. doi: 10.1378/chest.114.3.704.
- [8] Yaffe D, Koslow M, Haskiya H, Shitrit D. A novel technique
for CT-guided transthoracic biopsy of lung lesions: improved
biopsy accuracy and safety. Eur Radiol 2015;25:3354-60. doi:
10.1007/s00330.015.3750-z.
- [9] Çubuk R, Tasalı N, Midi A, ve ark. Akciğer lezyonlarında
bilgisayarlı tomografi eşliğinde transtorasik aspirasyon biopsi
sonuçları; işlem, komplikasyonlar ve tanı değeri. Maltepe Tıp
Dergisi 2009;1 32-7.
- [10] Shaffer K. Role of radiology for imaging and biopsy of solitary
pulmonary nodules. Chest 1999; 116:519-22. doi: 10.1378/
chest.116.suppl_3.519s.
- [11] Klein JS, Zarka MA. Transthoracic needle biopsy. Radiol
Clin North Am 2000;38:235-66. doi: 10.1016/s0033-
8389(05)70161-5.
- [12] Düzgün F, Tarhan S. Perkütan transtorasik akciğer ve kemik
biopsileri. Trd Sem 2015;3:182-91. doi:10.5152/trs.2015.172
- [13] Takeshita J, Masago K, Kato R, et al. CT-guided fine-needle
aspiration and core needle biopsies of pulmonary lesions:
A single-center experience with 750 biopsies in Japan. AJR
2015;204:29-34. doi: 10.2214/AJR.14.13151.
- [14] Boskovic T, Stanic J, Pena-Karan S, et al. Pneumothorax
after transthoracic needle biopsy of lung lesions under CT
guidance. J Thorac Dis 2014;6(S1):S99-S107.doi:10.3978/j.
issn.2072-1439.2013.12.08.
- [15] Drumm O, Eimear A. Joyce E A, Blacam C, et al. CTguided
lung biopsy: effect of biopsy-side down position on
pneumothorax and chest tube placement. Radiology 2019;
292:190-6. doi:10.1148/radiol.201.918.2321
- [16] Zeng L C, Liao H Q, Wu WB, et al. Effect of puncture sites on
pneumothorax after lung CT-guided biopsy. Medicine 2020;
99:e19656. doi: 10.1097/MD.000.000.0000019656
- [17] Yeow K M, Su I-H, Pan K T, et al. Risk factors of pneumothorax
and bleeding multivariate analysis of 660 CT-guided coaxial
cutting needle lung biopsies. Chest 2004;126:748-54. doi:
10.1378/chest.126.3.748
- [18] Arıba BK, Dingil G, Ahin G, et al. CT-guided transthoracic
biopsy: Factors in pneumothorax risk and diagnostic yield.
Nobel Medicus 2019; 7: 1: 37-41. doi: 10.1016/s0009-
9260(03)00221-6.
- [19] Aktas AR, Gozlek E, Yazkan R, et al. Transthoracic biopsy
of lung masses: Non technical factors affecting complication
occurrence. Thorac Can 2015 ;6:151-8. doi: 10.1111/1759-
7714.12156.
- [20] Chami HA, Faraj W, Yehia ZA, et al. Predictors of
pneumothorax after CT-guided transthoracic needle lung
biopsy: the role of quantitative CT. Clin Radiol 2015;70:1382-
7. doi: 10.1016/j.crad.2015.08.003