___

• [1] Rothan HA, Byrareddy SN. The epidemiology and pathogenesis of coronavirus disease (COVID-19) outbreak. J Autoimmun 2020; 109:102433.
• [2] Stübinger J, Schneider L. Epidemiology of coronavirus COVID-19: Forecasting the future incidence in different countries. Healthcare (Basel) 2020; 15:8. doi:10.3390/ healthcare8020099.
• [3] Center for Systems Science and Engineering (CSSE). Coronavirus COVID-19 Global Cases. Available online: Https://coronavirus.jhu.edu/map.html (accessed on 01 April 2022).
• [4] Ahn DG, Shin HJ, Kim MH, et al. Current status of epidemiology, diagnosis, therapeutics, and vaccines for novel Coronavirus disease 2019 (COVID-19). J Microbiol Biotechnol 2020; 30:313-24.doi:10.4014/jmb.2003.03011.
• [5] Jirjees F, Saad AK, Al Hano Z, Hatahet T, Al Obaidi H, Dallal Bashi YH. COVID-19 Treatment Guidelines: Do they really reflect best medical practices to manage the pandemic? Infect Dis Rep 2021; 13:259-84.
• [6] Hernández A, Papadakos PJ, Torres A, et al. Two known therapies could be useful as adjuvant therapy in critical patients infected by COVID-19. Rev Esp Anestesiol Reanim 2020;67:245-57. doi:10.1016/j.redar.2020.03.004.
• [7] Rowen RJ. Ozone and oxidation therapies as a solution to the emerging crisis in infectious disease management: a review of current knowledge and experience. Med Gas Res 2019; 9:232-7.doi:10.4103/2045-9912.273962.
• [8] Rowen RJ, Robins H. A plausible “Penny” costing effective treatment for Corona virus – ozone therapy. J Infect Dis Epidemiol 2020; 6:113.doi.org/10.23937/2474-3658/1510113
• [9] Bocci V. Ozone: A new medical drug. 2nd edition. Netherlands: Springer, 2011. doi.org/10.1007/978-90-481-9234-2
• [10] Martínez-Sánchez G, Schwartz A, Donna V D. Potential cytoprotective activity of ozone therapy in SARS-CoV-2/ COVID-19. Antioxidants 2020; 9:389.
• [11] Noori-Zadeh A, Bakhtiyari S, Khooz R, Haghani K, Darabi S. Intra-articular ozone therapy efficiently attenuates pain in knee osteoarthritic subjects: A systematic review and metaanalysis. Complement Ther Med 2019; 42:240-7.doi:10.1016/j. ctim.2018.11.023.
• [12] Carmona L. [Ozone therapy in rheumatic diseases: a systematic review]. Rheumatol Clin 2006; 2:119-23.doi:10.1016/S1699- 258X(06)73032-7.
• [13] Moreno-Fernández A, Macías-García L, Valverde-Moreno R, et al. Autohemotherapy with ozone as a possible effective treatment for Fibromyalgia. Acta Reumatol Port 2019; 44:244- 9.
• [14] Wang YY, Jin YH, Ren XQ, et al. Updating the diagnostic criteria of COVID-19 “suspected case” and “confirmed case” is necessary. Military Med Res 2020; 7:17. doi.org/10.1186/ s40779.020.00245-9
• [15] Vishnevetsky A, Levy M. Rethinking high-risk groups in COVID-19. Mult Scler Relat Disord 2020; 42:102139. doi:10.1016/j.msard.2020.102139.
• [16] Wang B, Li R, Lu Z, Huang Y. Does comorbidity increase the risk of patients with COVID-19?: Evidence from metaanalysis. Aging 2020; 12:6049-57. doi:10.18632/aging.103000.
• [17] Huang C, Wang Y, Li X, et al. Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China. Lancet 2020; 395:497-506.
• [18] Kunal S, Gupta K, Sharma SM, Pathak V, Mittal S, Tarke C. Cardiovascular system and COVID-19: perspectives from a developing country. Monaldi Arch Chest Dis 2020; 90. doi:10.4081/monaldi.2020.1305.
• [19] Muniyappa R, Gubbi S. COVID-19 pandemic, coronaviruses, and diabetes mellitus. Am J Physiol Endocrinol Metab 2020; 318:736-41.doi:10.1152/ajpendo.00124.2020.
• [20] Samuels JD. Obesity and severe COVID-19 disease: a strong association. Obesity (Silver Spring) 2020;28:1368. doi:10.1002/ oby.22866.
• [21] Diaz-Luis J, Menendez-Cepero S, Diaz-Luis A, Ascanio – Garcia Y. In vitro effect of ozone in phagocytic function of leucocytes in peripheral blood. J Ozone Ther 2015; 1.
• [22] Elvis AM, Ekta JS. Ozone therapy: A clinical review. J Nat Sci Biol Med 2011; 2:66-70. doi: 10.4103/0976-9668.82319.
• [23] Giovanni R, Marianno F, Luigi V. Oxygen-ozone immunoceutical therapy in COVID-19 outbreak. Ozone Ther 2020; 5:9014
• [24] Wang Z, Zhang A, Meng W, et al. Ozone protects the rat lung from ischemia-reperfusion injury by attenuating NLRP3- mediated inflammation, enhancing Nrf2 antioxidant activity and inhibiting apoptosis. Eur J Pharmacol 2018; 835:82-93. doi:10.1016/j.ejphar.2018.07.059.
• [25] Cespedes-Suarez J, Martin-Serrano Y, Carballosa-Peña M, Dager-Carballosa D. The immune response behavior in HIVAIDS patients treated with Ozone therapy for two years. J Ozone Ther 2018; 2:7.
• [26] Cespedes-Suarez J, Martin-Serrano Y, Carballosa- Peña M, Dager-Carballosa D. Response of patients with chronic hepatitis B in one year of treatment with major autohemotherapy. J Ozone Ther 2018; 2:9.
• [27] Zaky S, Kamel S, Hassan M, et al. Preliminary Results of Ozone Therapy as a Possible Treatment for Patients with Chronic Hepatitis C. Journal of alternative and complementary medicine 2011; 17:259-63.
• [28] Rowen R, Robins H, Carew K, Kamara M, Jalloh M. Rapid resolution of hemorrhagic fever (Ebola) in Sierra Leone with ozone therapy. Afr J Infect Dis 2015; 10:49.
• [29] Cattel F, Giordano S, Bertiond C, et al. Ozone therapy in COVID-19: A narrative review. Virus Res 2021; 291:198207.