Tülay ÖRKİ, Halide OĞUŞ, Rezzan YALTIRIK, Atakan ERKILINÇ, Füsun GÜZELMERİÇ, Deniz AVAN, Canan GÜLER, Tuncer KOÇAK

Development of Heparin Resistance During Coronary Artery Bypass Grafting Operation

Bu yazıda, kardiyopulmoner bypass sırasında karşılaşılan heparin direncine sahip bir olguyu ve tedavisini sunuyoruz. Koroner arter bypass greft cerrahisi planlanan hastaya güvenli aortik kanulasyon ve kardiyopulmoner bypass için gerekli olan aktive pıhtılaşma zamanına ulaşabilmek için 725.000 IU heparin ve 2 unite taze donmuş plazma verildi. Hastada önceki heparin tedavisine bağlı olarak heparin direnci gelişmiş olduğu düşünüldü. Taze donmuş plazma ile tedavi etmek heparinin etkinliğini yerine getirdi.

Anahtar Kelimeler:

Kardiyopulmoner bypass, heparin direnci, aktive pıhtılaşma zamanı, taze donmuş plazma

Koroner Arter Bypass Greftleme Ameliyatı Sırasında Gelişen Heparin Direnci

In this paper we aimed to present a case and its treatment with the resistance of heparin before during cardiopulmonary bypass. 725.000 IU of heparin and 2 units of fresh frozen plasma were administered to patient undergoing coronary artery bypass graft surgery to reach required activated clotting time for secure aortic cannulation and cardiopulmonary bypass. Heparin resistance was considered to be improved depending on the previous heparin treatment. The effectiveness of heparin fulfilled with the treatment of fresh frozen plasma.

Keywords:

cardiopulmonary bypass, heparin resistance, activated clotting time, fresh frozen plasma,

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