Hasan TUNAZ, M. Kubilay ER, A. Arda IŞIKBER

The Combine Effects of Eicosanoid Biosynthesis Inhibitors and Different Isolates of Metarhizium anisopliae (Metschn.) and Beauveria bassiana (Balsamo) (Deuteromycota: Hyphomycetes) on the Mortality of Spodoptera littoralis (Boisduval) (Lepidoptera: Noctuidae) Larvae

The effects of entomopathogen fungus isolates on the mortality ofSpodoptera littoralis (Boisduval) (Lepidoptera: Noctuidae) larvaewere increased and accelerated when co-administered with eicosanoidinhibitors (EBIs) (Dexamethasone, Indomethacin, EsculetinPhenidone Ibuprofen and Naproxen). The mode of action of thesecompounds are different. When eicosanoid inhibitors were applied toS. littoralis larvae together with entomopathogenic fungus isolates(Beauveria 6646 and Metarhizium 3293), they accelerated deaths ofthe insect and consequently increased mortality rates. In addition,when different doses of Phenidone, one of the eicosanoid inhibitors,were administered to the larvae with the fungal isolates, there was asignificant increase in mortality due to the dose of Phenidone. Theseresults showed that the application of eicosanoid inhibitors withfungal agents to S. littoralis larvae increased the effectiveness of thesepotential microbial control agents.

Metarhizium Anisopliae ve Beauveria Bassiana'nın Farklı İzolatlarının Eikosanoid Biyosentezi İnhibitörleri ile Birlikte Spodoptera Littoralis Larvalarına Uygulandığında Larvalar Üzerindeki Ölüm Etkisi

Entomopatojen fungus izolatlarının Spodoptera littoralis (Boisduval) (Lepidoptera: Noctuidae) larvalarının ölümü üzerindeki etkileri eikosanoid inhibitörleri (EBI'ler) (Deksametazon, İndometasin, Esculetin Fenidon Ibuprofen ve Naproksen) ile birlikte larvalara uygulandığında, larvaların ölüm oranı artmış ve hızlanmıştır. Eikosanoid inhibitörlerinin etki mekanizması birbirlerinden farklıdır. Entomopatojen fungus izolatları (Beauveria 6646 ve Metarhizium 3293) ile eikosanoid inhibitörleri birlikte S. littoralis larvalarına uygulandığında, böceğin ölüm oranlarını önemli derecede artırdığı gibi aynı zamanda böcek ölümleri hızlanmıştır. Ek olarak, bahsedilen fungus izolatları ile larvalara farklı dozlarda eikosanoid inhibitörlerinden Phenidone uygulandığında, Phenidone dozuna bağlı olarak larva ölüm oranında önemli bir artış olmuştur. Bu sonuçlar, eikosanoid inhibitörlerinin fungal etmenlerle birlikte S. littoralis larvalarına uygulanmasının, potansiyel mikrobiyal kontrol etmenlerinin bu zararlı üzerinde etkinliğini arttırdığını göstermiştir.

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