Harun ÇIFTÇI, Çiğdem-ER ÇALIŞKAN, Fatih-KAR, Ahmet-ÖZKAYA, Kenan-GÜÇLÜ

Alüminyuma Maruz Kalmış Erkek Sıçanlarda Nar Suyunun Hepato-Nefrotoksisite Üzerine Etkilerinin Değerlendirilmesi

Nar suyunun AlCl3 kaynaklı hepato-nefrotoksisiteye olan etkilerini analiz etmek için sıçan serumundaki elektrolit seviyeleri, böbrek ve karaciğer fonksiyon testi ve lipid profili gibi biyokimyasal parametreleri amaçlanmıştır. Yirmi sekiz wistar albino sıçan; kontrol (Grup I), nar suyu (4 ml/kg) (Grup II), AlCl3 (8,3 mg/kg) (Grup III) ve nar suyu + AlCl3 (Grup IV) şeklinde dört gruba ayrılmıştır. Alüminyum toksisitesi ve nar suyunun koruyucu etkisi elektrolit düzeyleri açısından Mg ve Cl hariç gruplar arasında istatistiksel olarak farklı bulunmamıştır (p

Evaluation of The Effects of Pomegranate Juice on Hepato-Nephrotoxicity in Male Rats Exposed to Aluminum

We aimed to measure biochemical parameters in rat serum such as electrolyte levels, kidney and liver function test, and lipid profile to analyze the effects of pomegranate juice towards AlCl3-induced hepato-nephrotoxicity. The twenty-eight wistar albino rats divided into four groups; control (Group I), pomegranate juice (4 ml/kg) (Group II), AlCl3 (8.3 mg/kg) (Group III) and pomegranate juice + AlCl3 (Group IV). Aluminum toxicity and the protective effect of pomegranate juice did not statistically different among groups in electrolyte levels, except for Mg and Cl (p

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