Lütfi ÖCAL, Sinan CERŞİT, Ender Özgün ÇAKMAK, Hakan ÇAKIR, Aslı ÖCAL, Hayati EREN

ST-Segment Yükselmeli Miyokardiyal Enfarktüslü Hastalarda Serum Sodyum Düzeyleri: Hastane İçi ve Uzun Dönem Klinik Sonuçları Üzerine Etkileri

Giriş: Akut miyokardiyal enfarktüslü hastalarda serum sodyum düzeyleri ve klinik sonuçlar arasındaki ilişki ile ilgili çelişkili sonuçlar bulunmaktadır. Bu çalışmada, ST-segment yükselmeli miyokardiyal enfarktüslü (STYME) hastalarda serum sodyum düzeylerinin hastane içi ve uzun dönem klinik sonuçları üzerine etkileri araştırılmıştır. Hastalar ve Yöntem: Primer perkütan koroner girişim uygulanan 1840 STYME hastası (ortalama yaş 57.3 ± 11.8; erkek %79.7) çalışmaya dahil edilmiştir. Hastalar başvurudaki serum sodyum düzeylerine göre dört gruba ayrıldıktan sonra bazal karakteristik özellikleri ve klinik sonuçları karşılaştırılmıştır. Bulgular: Hastane içi ölüm, kardiyojenik şok, ventriküler aritmi, akut böbrek hasarı ve majör kardiyak olaylar açısından belirgin farklılıklar bulunmamıştır. Ayrıca, üç yıllık takip sonrasında; uzun dönem ölüm ve majör kardiyak olaylar açısından benzer sonuçlar bulunmuştur. Sonuç: Geniş ölçekli bu çalışmada, STYME olan hastaların serum sodyum düzeyleri ile hastane içi ve uzun dönem klinik sonuçlar arasında ciddi bir ilişki gözlenmemiştir.

Serum Sodium Levels in Patients with ST-Segment Elevation Myocardial Infarction: Its Effects on In-Hospital and Long-Term Clinical Outcomes

Introduction: There are some conflicting results in the association of serum sodium level with clinical outcomes in patients with acute myocardial infarction. The aim of this study was to investigate the effect of serum sodium levels on in-hospital and long-term outcomes in patients with ST-segment elevation myocardial infarction (STEMI). Patients and Methods: A total of 1840 patients with STEMI (mean age 57.3 ± 11.8; men 79.7%) who underwent primary percutaneous coronary intervention were included to the study. Baseline characteristics and outcomes were compared among the patients by admission serum sodium level and categorized accordingly; Q1, Q2, Q3 and Q4. Results: There was not a significant difference regarding in-hospital mortality, cardiogenic shock, ventricular arrhythmia, acute kidney injury and major adverse cardiac events. Furthermore, after a follow-up period of 3-years; there was not a significant difference regarding long-term mortality and major adverse cardiac events. Conclusion: In this large-scale study, we did not observe a significant association of serum sodium level with in-hospital and long-term clinical outcomes in patients with STEMI.

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ISSN: 2149-2972
Yayın Aralığı: Yılda 3 Sayı
Başlangıç: 1990
Yayıncı: Sağlık Bilimleri Üniversitesi, Kartal Koşuyolu Yüksek İhtisas Eğitim ve Araştırma Hastanesi