Mehmet Ata AKIL, Mehmet Zihni BİLİK, Halit ACET, Senem Yaman TUNÇ, Yahya İSLAMOĞLU, Hasan KAYA, Sait ALAN, Faruk ERTAŞ, Mesut AYDIN

Mean Platelet Volume and Neutrophil Lymphocyte Ratio as New Markers of Preeclampsia Severity

Giriş: Bu çalışmada, hematolojik parametrelerin ölçümleri ile preeklamptik kadınlarda hipertansiyon şiddetini tahmin etmenin mümkün olup olmadığını araştırdık.Hastalar ve Yöntem: İki yüz altmış bir preeklamptik ve 51 normal gebe kadın çalışmaya alındı. Preeklampsi olguları hafi f ve ağır preeklampsi olarak sınıfl andırıldı.Bulgular: Doğum sonrası sonuçlar karşılaştırıldığında, preeklamptik kadınların trombosit sayıları düşük, ortalama trombosit hacimleri ve nötrofi l lenfosit oranları yüksekti (sırasıyla; p< 0.001, p< 0.001 ve p< 0.001). Çoklu lineer regresyon analizinde, ortalama trombosit hacmi ve nötrofi l lenfosit oranı hipertansiyon şiddeti ile bağımsız bir şekilde korelasyon gösterdi (sırasıyla; ?= 0.25, p< 0.001 ve ?= 0.31, p< 0.001).Sonuç: Hem ortalama trombosit hacmi hemde nötrofi l lenfosit oranı preeklamptik gebelerde hipertansiyonun şiddetini öngörmede bağımsız birer belirleyici olarak kullanılabilir

Ortalama Trombosit Hacmi ve Nötrofi l Lenfosit Oranı: Preeklampsinin Ciddiyetinin Yeni Belirteçleri

Introduction: This study was undertaken to examine the role of hematological parameters in predicting the severity of hypertension in pre-eclamptic women.Patients and Methods: Two hundred sixty-one pre-eclamptic women and fi fty-one women with normal pregnancy were included in the study. The severity of preeclampsia was classifi ed as mild or severe. Results: Compared to post-delivery period, pre-eclamptic females had lower platelet count, raised mean platelet volume and raised neutrophil lymphocyte ratio (p< 0.001, p< 0.001, p< 0.001, respectively). Multiple linear regression analysis showed an independent correlation between the severity of hypertension and mean platelet volume as well as the neutrophil lymphocyte ratio (?= 0.25, p< 0.001; ?= 0.31, p< 0.001, respectively).Conclusion: Both mean platelet volume and neutrophil lymphocyte ratio emerged as independent predictors of the severity of hypertension in preeclampsia

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ISSN: 2149-2972
Yayın Aralığı: Yılda 3 Sayı
Başlangıç: 1990
Yayıncı: Sağlık Bilimleri Üniversitesi, Kartal Koşuyolu Yüksek İhtisas Eğitim ve Araştırma Hastanesi