Süleyman Hilmi AKSOY, Oğuzhan BİRDAL, Işıl YURDAIŞIK

Koroner Baypas Ameliyatı Olacak Hastalarda SYNTAX Skorunun Karotis Plak Morfolojisi ile İlişkisi

Giriş: Karotis arter ultrason bulguları ile koroner arter hastalığı arasındaki ilişkiyi değerlendiren birçok çalışma olmasına rağmen karotis plak tipleri ve koroner lezyonların karmaşıklığı arasındaki ilişki değerlendirilmemiştir. Bu çalışmada, SYNTAX skoru ile karotis plak morfolojisi arasındaki ilişkinin incelenmesi amaçlanmıştır. Hastalar ve Yöntem: Çalışmada, 2015-2020 yılları arasında koroner arter baypas greft operasyonu öncesi karotis ultrasonu yapılan hastalar geriye dönük olarak tarandı. SYNTAX skoru, çevrim içi SYNTAX skor hesaplayıcısı (www.syntaxscore.com) ile iki bağımsız girişimsel kardiyolog tarafından hesaplandı. Ultrason ile karotis arter lezyonları şu şekilde sınıflandırıldı: fibroz, kalsifik ve mikst plaklar. Bulgular: İncelemeye toplam 407 hasta alınmıştır. Ortanca yaş 65 (58-71) yıl ve hastaların %81.6’sı erkektir. Plak türleri ve SYNTAX skoru arasındaki ilişkiyi test etmek için multinomial lojistik regresyon kullanılmıştır. SYNTAX skoru, hem sağda (Odds oranı 1.04, %95 CI 1.01-1.07, p= 0.006) hem de sol internal karotid arterde (Odds oranı 1.04, %95 CI 1.02-1.06, p= 0.004) kalsifiye plak ile ilişkilendirilmiştir. Bununla birlikte, SYNTAX skoru, fibröz (sağ için Odds oranı 0.97, %95 CI 0.94-1.01, p= 0.155 ve sol karotid arter için Odds oranı 0.99, %95 CI 0.96-1.02, p= 0.759) ve mikst plak ile ilişkili saptanmamıştır (Odds oranı 1.02, %95 CI 0.98-1.06, sağ için p= 0.168 ve sol karotid arter için Odds oranı 1.00, %95 CI 0.96-1.04, p= 0.791). Sonuç: SYNTAX skoru, karotis plak morfolojisi tahmini için bir fikir sağlayabilir. Özellikle yüksek SYNTAX skorlarının varlığı, daha fazla kalsifik karotis plakları ile ilişkili bulunmuştur.

The Relation of SYNTAX Score with Carotid Plaque Morphology in Patients Who Undergoing Coronary By-pass Surgery

Introduction: Although there are many studies assessing the relationship between carotid artery ultrasound findings and coronary artery disease, the relationship between carotid plaque types and the complexity of coronary lesions is not assessed. We aimed to examine the relationship between the SYNTAX score and carotid plaque morphology. Patients and Methods: We retrospectively screened patients who underwent carotid Ultrasound before the coronary artery bypass graft operation between 2015 and 2020. Syntax score was calculated by two independent interventional cardiologists with online SYNTAX score calculator (www.syntaxscore.com). The lesions of carotid arteries by ultrasound were classified as fibrous, calcific and mixed plaques. Results: A total of 407 patients were enrolled. Median age was 65 (58-71) years and 81.6% of patients were male. We used multinomial logistic regression to test the association between plaque types and syntax score. The syntax score was associated with calcified plaque both in right (odds ratio 1.04, 95% CI 1.01-1.07, p= 0.006) and left internal carotid artery (odds ratio 1.04, 95% CI 1.02-1.06, p= 0.004). However, the syntax score was not associated with fibrous (odds ratio 0.97, 95% CI 0.94-1.01, p= 0.155 for right and odds ratio 0.99, 95% CI 0.96-1.02, p= 0.759 for left carotid artery) and mixed plaque types (odds ratio 1.02, 95% CI 0.98-1.06, p= 0.168 for right and odds ratio 1.00, 95% CI 0.96-1.04, p= 0.791 for left carotid artery). Conclusion: SYNTAX score may provide an idea for carotid plaque morphology prediction. Especially higher SYNTAX score may be a predictor of calcific carotid plaque.

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ISSN: 2149-2972
Yayın Aralığı: Yılda 3 Sayı
Başlangıç: 1990
Yayıncı: Sağlık Bilimleri Üniversitesi, Kartal Koşuyolu Yüksek İhtisas Eğitim ve Araştırma Hastanesi