Belgin COŞKUN, Müge AYHAN, Elif Mukime SARICAOĞLU, Rahmet GÜNER, Esragül AKINCI, Turan BUZGAN, Bircan KAYAASLAN, Adalet AYPAK, Ayşe Yasemin TEZER TEKÇE, İmran HASANOĞLU, Ayşe KAYA KALEM, Fatma ESER, Yeşim AYBAR BİLİR, Burcu ÖZDEMİR

Monosit/ Yüksek Dansiteli Lipoprotein (MHR) ve COVID-19 Arasındaki İlişkinin Değerlendirilmesi

Amaç: COVID-19’da şiddetli hastalığı erken tanımak önemlidir. Monosit / yüksek dansiteli lipoprotein oranı (MHR), inflamasyon seyrini belirlemede kullanılan yeni bir belirteçtir. Bu çalışmada MHR ile COVID-19 seyri arasındaki ilişkiyi incelemek amaçlanmıştır. Materyal ve Metod: Laboratuvar ile konfirme edilmiş COVID-19 hastaları retrospektif olarak analiz edildi. Hastanemize başvuran hastanın ilk günki klinik semptomları, bulguları, ve laboratuvar sonuçları hastane bilgi işlem sisteminden taranarak kayıt altına alındı. Çalışmamıza toplam 301 hasta dahil edildi. Hastalar Dünya Sağlık Örgütü (DSÖ) klavuzu dikkate alınarak sınıflandırıldı. MHR hastaların hastaneye kabul edildiği ilk gün bakılan laboratuvar verileri kullanılarak hesaplandı. MHR ile COVID-19 şiddeti arasındaki ilişki değerlendirildi. Hasta verileri SPSS 25 (SPSS Inc., Chicago, IL, USA) kullanılarak analiz edildi. İstatistiksel olarak P

Anahtar Kelimeler:

COVID-19, Yüksek dansiteli lipoprotein, İnflamasyon, Monosit, Şiddetli Hastalık

The Evaluation of Relationship Between Monocyte/High-Density Lipoprotein Ratio (MHR) and COVID-19

Objective: Early diagnosis is important for severe diseases in COVID-19. Monocyte/high dansity lipoprotein ratio (MHR) is a new prognostic marker indicating inflammation. We aimed to investigate the relationship between MHR and diseases severity in COVID-19. Materials and Methods: Patients with laboratory confirmed COVID-19, were retrospectively analyzed. Clinical symptoms, signs and laboratory data on the first day of hospitalization were obtained from medical records of hospital. The clinical data of 301 patients were included in study. Cases were diagnosed on the basis of interim guidance of World Health Organization (WHO). Patients were classified into two groups as non-severe COVID-19 and severe COVID-19. MHR were calculated with laboratory data on the first day of hospitalization. The relationship between MHR level and COVID-19 severity was evaluated. Statistical analysis of the data was performed by using SPSS 25 (SPSS Inc., Chicago, IL, USA) package program. Statistical significance level was accepted as p

Keywords:

COVID-19, High-Density lipoprotein, Inflammation, Monocyte, Severe Diseases,

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ISSN: 1309-3878
Yayın Aralığı: Yılda 3 Sayı
Başlangıç: 2009
Yayıncı: Düzce Üniversitesi Tıp Fakültesi Aile Hekimliği AD adına Yrd.Doç.Dr.Cemil Işık Sönmez