Ahmet Cihat TUNÇ, Fatih Mehmet BİRDANE, Cangir UYARLAR, Fulya ALTINOK YİPEL, Eyüp Eren GÜLTEPE, Durmuş Fatih BAŞER, Abuzer ACAR

Geçiş Dönemindeki Süt İneklerinde Damar İçi Novacoc® Uygulamasının Metabolik Profil Üzerine Etkileri

Sunulan çalışma süt ineklerine doğuma üç hafta kala, haftalık olarak yapılan damar içi Novacoc® enjeksiyonunun, erken laktasyon dönemde bazı kan, metabolizma ve bağışıklık parametreleri üzerine etkisini incelemek amacıyla yürütülmüştür. Çalışmada, 20 adet Holştayn ırkı süt ineği rastgele olarak kontrol ve uygulama olmak üzere iki gruba ayrılmıştır. Çalışma boyunca uygulama grubundaki ineklere, doğuma üç hafta kala başlayıp doğuma kadar devam edecek şekilde, her haftanın ilk üç günü uygulamak üzere günde 200 ml Novacoc® (Metamizol Sodyum; 40 mg, Asetilmetiyonin 40 mg, Kafein 3,5 mg, Kalsiyum Glukonat 100 mg, Magnezyum Glukonat 10 mg, Sodyum Dihidrojen Fosfat Dihidrat 4,02 mg, Glikoz monohidrat 200; İnterhas®, Türkiye) damar içi yavaş infüzyon şeklinde uygulanmıştır. Buzağılama günü “0 (sıfır)” kabul edilerek; tüm ineklerin kuyruk venasından (V.Coccygea) -21, -14, -7, 0, 7, 14, 21. günlerde hematolojik ve biyokimyasal analizler için örnekler alınmıştır. Kan total kolesterol, HDL, Trigliserit ve glukoz seviyeleri doğum sonrasında bazı günlerde istatiksel ancak tamamında sayısal olarak yüksek bulunmuş, NEFA ve BHBA seviyeleri ise düşük bulunmuştur. Öyle ki kontrol grubunun NEFA ve BHBA değerleri subklinik ketozis düzeyinde seyretmiştir. Bu verilere ek olarak laktasyonun ilk üç haftası süt verimi her iki grupta da benzer iken pik süt verimi uygulama grubunda anlamlı şekilde yüksek bulunmuştur.

Anahtar Kelimeler:

Novacoc®, Metabolik Profil, Süt İnekleri, NEFA, BHBA

The Effects of Intravenous Novacoc® Treatment on Metabolic Profiles During the Transition Period of Dairy Cows

This study was performed to evaluate the effect of weekly intravaneous administration of Novacoc®, 3 weeks before parturition on some hematological, metabolism, and immune parameters on early lactation period in dairy cows. In this study 20 random Holstein dairy cows has been used and divided into two groups as control group and the treatment group. The treatment started 3 weeks before parturation and ended parturaiton. The treatment has been made in first three days of each week. The animals in the treatment group were administered daily Novacoc®, 200 ml (Metamizol Sodium; 40 mg, Acetyl methionine 40 mg, Caffeine 3,5 mg, Calcium Gluconate 100 mg, Magnesium Gluconate 10 mg, Sodium Dihydrogen Phospate Dhydrate 4,02 mg, Glucose monohydrate 200; İnterhas®, Türkiye) as intravenous slowly infusion on first 3 days of each weeks during last 3 weeks of prepartum period and first 3 weeks of postpartum period. Parturition day was planned as day “0 (zero)”; blood samples were collected on days -21, -14, -7, 0, 7, 14, 21 from V. Coccygea of all cows. Total cholesterol, HDL, triglyceride, and glucose levels were significantly higher on some postpartum days; However, NEFA and BHBA levels were found decreased. NEFA and BHBA levels in the control group were detected as subclinical ketosis levels. In addition to this results, the milk yields of each group were measured as same during first 3 weeks of lactation, but peak milk yield on the treatment group increased significantly.

Keywords:

Novacoc®, Metabolic Profile, Dairy Cows, NEFA, BHBA,

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