Pınar KESİK, Can ACIPAYAM, Fatih TEMİZ, Nursel YURTTUTAN, Ahmet Gökhan GÜLER, Hamide SAYAR, Tuğba KANDEMİR GÜLMEZ

PATOLOJİK LENFADENOPATİLERDE KLİNİK, LABORATUAR, ULTRASON BULGULARI İLE HİSTOPATOLOJİ SONUÇLARININ KARŞILAŞTIRILMASI

Amaç: Lenfadenopatilerde malignite çıkma olasılığı %1-3 oranındadır ve en sık lenfomalar gözlenir. Ultrasonografi ayırıcı tanıda hekime bazı bulguları ile malignite yönünde yardımcı olabilir. Tanısı kesinleştirilememiş, malignite düşünülen vakalarda biyopsi yapılması esastır. Bu çalışmada patolojik lenfadopatili hastaların sosyo demografik verileri klinik laboratuvar, ultrason bulguları ve histopatoloji sonuçlarının karşılaştırılması hedeflenmiştir. Yöntemler: Bu çalışmada Kahramanmaraş Sütçü İmam Tıp Fakültesi Hastanesi’ne Ocak 2014 ve Eylül 2016 tarihleri arasında başvuran 857 lenfadenopatili hastadan (328 kız-529 erkek) 50 adet (39’u erkek, 11’i kız) patolojik lenfadenopatili hasta geriye dönük olarak değerlendirildi. Bulgular: Patolojik lenfadenopati tanılı 50 hastanın yaşları 12-192 ay arasında değişmektedir. Hastaların 24’ünde lenfadenopati boyutu 3 cm’nin üzerindeydi. Lenfadenopatilerden 35’i servikal, 15’i ise servikal dışı lokalizasyona sahipti. Bu hastalardan 35’ine reaktif, 15’ine ise non-reaktif USG sonucu saptandı. Hastalardan 38’inde benign hastalık, 12’sinde ise malignite saptandı. Yapılan istatistiksel analizler neticesinde patoloji sonuçları ile USG özelliği arasında ve aynı zamanda lenfadenopati boyutu ile USG’de tespit edilen boyut arasında anlamlı bir ilişki saptandı (p<0,05). Çalışmamız da bening ve malign olanların USG özelliği ve ateş açısından karşılaştırılmasında benign olanların 12’sinde (%31,6), malign olanların ise 9’unda (%75) ateş söz konusu olup gruplar arasında ateş varlığı açısından anlamlı farklılık vardır (p<0,05). Sonuç: Lenfadenopati ile başvuran olgularda öykü ve fizik incelemeden sonra lenfadenopatinin ciddi bir hastalığın belirtisi olup olmadığı araştırılmalıdır.

Anahtar Kelimeler:

Lenfadenopati, patoloji, Ultrasonografi

COMPARISON OF HISTOPATHOLOGY RESULTS WITH CLINICAL, LABORATORY, ULTRASONOGRAPHIC FINDINGS IN PATIENTS WITH PATHOLOGIC LYMPHADENOPATHY

OBJECTIVE: The likelihood of malignancy in lymphadenopathies is 1-3% and the mostly lymphomas are seen. Ultrasonography may be helpful in malignancy with some findings in the differential diagnosis of the disease. In cases where malignancy is suspected, which the diagnosis is incomplete, the biopsy is required. In this study, we aimed to compare sociodemographic data of clinical, laboratory, ultrasound findings and histopathology of patients with pathologic lymphadenopathy.MATERIAL AND METHODS: For this purpose, among 857 lymphadenopathic patients (328 females-529 males) who were admitted to Kahramanmaras Sütçü İmam University Medical Faculty Hospital between January 2014 and September 2016, 50 patients (39 male, 11 female) were retrospectively evaluated.RESULTS: The ages of the 50 patients included in the study ranged from 12 months to 192 months. Lymphadenopathy size was over 3 cm in 24 of the patients. Of the lymphadenopathies, 35 had cervical and 15 had non-cervical localization. Among these patients, it was diagnosed with reactive in 35 patients and non-reactive in 15 patients. Of the patients, 38 had benign disease and malignancy was observed in 12 patients. As a result of the statistical analyzes, a significantly correlated relationship was found between pathology results and ultrasonography as well as lymphadenopathy size and the size observed in ultrasonography (p<0.05). In our study, in terms of comparison for usg feature and fever between benign and malign, fever was seen in 12 (31.6%) of benign patients, and 9 (75%) of malignant patients, as there was a significant difference between groups in terms of the presence of fever (p <0.05).CONCLUSIONS: After examining medical history and physical examination of the patients with lymphadenopathy, lymphadenopathy should be investigated for signs of a serious illness.

Keywords:

Lymphadenopathy, Pathology, Ultrasonography,

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