Adil DOĞAN, Veysel BURULDAY, Murat ALPUA

KRONİK DÖNEMDE İNME GEÇİRMİŞ HASTALARIN OLFAKTÖR BULBUS HACİMLERİNİN VE OLFAKTÖR SULKUS DERİNLİKLERİNİN DEĞERLENDİRİLMESİ

AMAÇ: Bu çalışmada, kronik dönemdeki inme geçirmiş hastaların olfaktör bulbus (OB) hacimleri ve olfaktör sulcus (OS) derinliğini değerlendirmek amaçlandı. GEREÇ VE YÖNTEM: Bu çalışma retrospektif ve olgu kontrol çalışması olarak planlandı. Kronik dönemde (>6 ay) inme geçirmiş hastaların OB hacimleri ve OS derinliği ölçümü, manyetik rezonans görüntüleme 1.5-tesla MRG sistemi (Philips MRI Systems, Achieva Release 3.2 Level 2013-10-21, Philips Medical) ile standart kafa coili kullanılarak yapıldı. OB hacim ve OS derinliği ölçümleri, yağ baskılı T2 koronal kesitler kullanılarak yapıldı. İnmeli hastaların verileri sağlıklı kontrol grubu ile karşılaştırıldı. BULGULAR: Çalışmaya, yaş ortalaması 47.7±10.7 yıl olan 45 (21 erkek, 24 kadın) inme geçirmiş hasta ile yaş ortalaması 44.5±8.7 yıl olan 45 (19 erkek-26 kadın) sağlıklı kontrol dahil edildi. İnme grubu ile kontrol grubu karşılaştırıldığında sağ (34.8±10.1 vs. 44.0±7.4 mm3) ve sol OB (34.9±10.0 vs. 49.1±6.2 mm3) hacimlerinin ortalama değerlerinin inme geçirmiş grupta kontrollere göre belirgin olarak azaldığı görüldü. Olfaktör sulkus derinliği ise sağda gruplar arasında değişiklik göstermezken (7.0±0.0 vs. 7.0±0.7 mm) ve solda inmeli grupta daha yüksek bulundu (7.1±0.9 vs. 6.7±0.6 mm). SONUÇ: İnme sonrası kronik dönemdeki hastalarda olfaktör bulbus hacimlerinin azaldığı görüldü.

EVALUATION OF THE OLFACTORY BULB VOLUME ANF OLFACTORY SULCUS DEPTH IN PATIENTS WITH CHRONIC STROKE

OBJECTIVE: The aim of this study was to evaluate the olfactory bulb (OB) volume and olfactory sulcus (OS) depth in patients with chronic stroke. MATERIAL AND METHODS: This study was designed as a case-control and retrospective study. OB volumes and OB depth of the patients with chronic stroke (>6 months) were measured using a 1.5 tesla MRI machine (Philips MRI Systems, Achieva Release 3.2 Level 2013-10-21, Philips Medical) with a standard head coil. OB volumes and OS depth were measured by using fat suppressed T2 coronal images. The data of the stroke patients were compared to the healthy control subjects. RESULTS: The study included 45 (21 male/24 female) post-stroke patients with the mean age of 47.7±10.7 years and 45 (19 male/26 female) healthy control subjects with the mean age of 44.5±8.7 years. Right (34.8±10.1 vs. 44.0±7.4 mm3) and left (34.9±10.0 vs. 49.1±6.2 mm3) OB volumes were significantly lower in the stroke group than in the control group. Olfactory sulcus depth was similar between the groups on the right side (7.0±0.0 vs. 7.0±0.7 mm), however it was higher in the stroke group on the left side (7.1±0.9 vs. 6.7±0.6 mm). CONCLUSIONS: Patients with chronic stroke seem to have decreased OB volumes compared to the healthy control.

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