MUSTAFA ÖZTÜRK, Murat DEDE, Hakan ÇOKSÜER, Uğur KESKİN, Cihangir Mutlu ERCAN, İskender BAŞER, Ahmet AKAR

Mikozis Fungoides ve Gebelik: Vaka Sunumu

Amaç: Bu vaka sunumunda mycozis fungoides’in (MF) gebelik üzerine etkisini ve gebelikte mycozis fungoides paternini ve literatürün gözden geçirilmesi amaçlanmıştır. Vaka: Hasta 30 yaşında, gravidası 1, paritesi 1 idi. Kliniğimize 7 haftalık gebelikle başvurdu ve tedavisine gebelik nedeniyle ara verildi. Hastaya Psoralen ve ultraviyole -A light (PUVA) tedavisi uygulandı. Sonuç: Gebeliğe MF’in etkisi, sınırlı vaka sayısı nedeni ile tam bilinmemektedir ve vakamızda MF’nin önemli yan etkisi gözlenmemiştir. Fakat gebelikte MF‘in etkisi ve gebelik süresince MF tedavisi ile ilgili daha geniş çalışmalara ihtiyaç vardır

Anahtar Kelimeler:

Mikozis Fungoides, gebelik

Mikozis Fungoides ve Gebelik: Vaka Sunumu

Keywords:

-,

PDF

___

Martinez W, Pozo J, Vazquez J: Cutaneous T-cell lymphoma presenting as disseminated, pigmented, purpura like eruption. Int J Dermatol. 2001; 40: 140
Criscione, VD, Weinstock, MA. Incidence of cutaneous T-cell lymphoma in the United States, 2002. Arch Dermatol. 2007; 143:854-856.
Bradford, PT, Devesa, SS, Anderson, WF, Toro, JR. Cutaneous lymphoma incidence patterns in the United States: a population-based study of 3884 cases. Blood. 2009; 113:5064-5067.
Hoppe, RT, Wood, GS, Abel, EA. Mycosis fungoides and the Sezary syndrome: pathology, staging, and treatment. Curr Probl Cancer. 1990; 14:293-296.
Morales, MM, Olsen, J, Johansen, P, et al. Viral infection, atopy and mycosis fungoides: a European multicentre case-control study. Eur J Cancer. 2003; :511-515.
Barnhill RL, Braverman IM: Progression of pigmented purpura-like eruptions to mycosis fungoides: Report of three cases. J Am Acad Dermatol. 1988; 19: 25-31.
Camisa C, Aulisio A: Pustular mycosis fungoides. Cutis. 1994; 54: 202-207.
Dalton JA, Yag-Howard C, Messina JL, Glass LF. Cutaneous T-cell lymphoma. Int J Dermatol. 1997; 36: 809.
Latkowski JA, Heald P. Cutaneous T Cell Lymphomas. In: Freedberg IM, Eisen AZ, Wolff K, (eds). Fitzpatrick’s Dermatology in General Medicine, Vol 2, 6th ed. New York: Mc Graw Hill 2003; 52:1537
Pimpinelli, N, Olsen, EA, Santucci, M, et al. Defining early mycosis fungoides. J Am Acad Dermato.l 2005; 53:1053-1058.
Olsen, E, Vonderheid, E, Pimpinelli, N, et al. Revisions to the staging and classification of mycosis fungoides and Sezary syndrome: a proposal of the International Society for Cutaneous Lymphomas (ISCL) and the cutaneous lymphoma task force of the European Organization of Research and Treatment of Cancer (EORTC). Blood. 2007; 110:1713-1718.
Vonderheid EC, Dellatorre DL, Van Scott EJ. Prolonged remission of tumor-stage mycosis fungoides by topical immunotherapy. Arch Dermatol. ; 117: 586–589. Amitay-Layish I, David M, Kafri B, Barzilai A, Feinmesser M, Hodak E. Early-stage mycosis fungoides, parapsoriasis en plaque, and pregnancy. Int J Dermatol. 2007;46:160-165.
Willemze R, Jaffe ES, Burg G, et al. WHO-EORTC classification for cutaneous lymphomas. Blood. 2005; : 3768–3785.
Kroumpouzos G, Cohen LM. Dermatoses of pregnancy. J Am Acad Dermatol. 2001; 45 : 1–19.
Castelo-Branco C,Torne A,Cararac V et al. Mycosis fungoides and pregnancy Oncol Rep. 2001;8:197-199
Echols KT,Gilles JM ,Diro M Mycosis fungoides in pregnancy: remission after treatment with alpha – interferon in case refractory to conventional therapy : a case report.J.Maternal Fetal Med. 2001;10:68-70
Amtay-LayishI,David M,Kafri B et al. Early stage mycozis fungoides, parapsoriasis en plaque , and pregnancy Int J. Dermatol. 2007;46:160-165
Gunnerskag JG, Arch dermatologist. 1993;129:320