Kas İskelet Sistemi Yaralanmalarında Plateletten Zengin Plazma Tedavisi

Kas iskelet sistemi yaralanmaları uzun dönem şiddetli ağrı ve fiziksel özürlülüğün en sık nedenlerinden biri olup, dünya genelinde yüz milyonlarca kişiyi etkilemektedir. Yara iyileşmesi faktörlerinin normal doku yapısında ve doku hasarına verilen cevapta kompleks bir regulasyona sahip olduğunu ve hasarlı dokunun iyileşmesinde önemli ve etkin rol üstlendiklerini ortaya çıkarmıştır. Koagulasyon kaskadında önemli rolleri ile bilinen plateletlerin, içerdikleri büyüme faktörleriyle anlaşılmıştır. Plateletleri konsantre ederek suprafizyolojik dozlarda büyüme faktörü elde etmek, yara iyileşmesinin hızlandırılması ve daha iyi fonksiyonel düzelme sağlamak, plateletten zengin plazma tedavisinin (PZP) esasını oluşturmaktadır. Lateral epikondilit, aşil tendiniti, rotator tendon lezyonları, ligament ruptürleri, kas yaralanmaları, osteoartrit gibi kas iskelet sistemini ilgilendiren çok çeşitli durumlarda kullanılan PZP ortopedi, fiziksel tıp ve rehabilitasyon, spor hekimliği branşlarının yanında, diş hekimliği, plastik cerrahi, dermatoloji, nöroloji ve oftalmoloji gibi birçok branşın da ilgi alanına girmektedir. Henüz yeni sayılabilecek bu tedavi şeklinin uygulamasında tam bir standardizasyon bulunmamaktadır. Farklı ticari kitler ile farklı ürünler elde edilebilmekte, bu da klinik çalışmalarda sorunlara yol açmaktadır. Bununla birlikte, PZP tedavisinin etkinliğinin değerlendirildiği klinik çalışmalarda umut vadeden sonuçlar elde edilebilmektedir. Yara iyileşmesinde sonucu önceden tahmin edilebilen, hızlı doku tamiri ve fonksiyonel hedeflenmektedir. Bu bağlamda PZP önemli bir basamak teşkil etmektedir

Anahtar Kelimeler:

Kas-iskelet sistemi yaralanmaları, plateletten zengin plazma, yara iyileşmesi

Kas İskelet Sistemi Yaralanmalarında Plateletten Zengin Plazma Tedavisi

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