Gülşah Selvi DEMİRTAŞ, Ömer DEMİRTAŞ, Kemal ÖZTEKİN, Fatih ŞENDAĞ, Onur BİLGİN

Antimüllerian Hormon ve İntrauterin İnseminasyon Sikluslarında Ovarian Yanıt: Prospektif Çalışma

Amaç: Çalışmamızın amacı, intrauterin inseminasyon sikluslarında, over rezervini değerlendirmede antimüllerian hormon ile diğer rezerv belirteçlerini karşılaştırarak antimüllerian hormonun güvenilirliğinin araştırılmasıdır. Gereç ve Yöntem: Eylül 2009 ile Mayıs 2011 tarihleri arasında Ege Üniversitesi Tıp Fakültesi Kadın Hastalıkları ve Doğum Kliniği İnfertilite Bölümü’ne başvuran ve intrauterin inseminasyon yapılan 80 hasta değerlendirilmiştir. Bu hastaların 9’unda polikistik over ve hipotalamohipofizer yetmezlik tanısı konulması üzerine çalışma grubuna dahil edilmediler ve çalışmaya dahil edilen 71 hasta klomifen sitrat ve gonadotropin kullanılan hastalar olarak iki gruba ayrıldı. Her iki grup, over yanıtına göre kendi arasında düşük, normal ve fazla over yanıtı olarak ayrılarak gruplar bazal AMH, LH, FSH, E2, PRL, yaş, antral follikül sayısı, gebelik açısından karşılaştırıldı. Bulgular: Klomifen sitrat ve gonadotropin verilen gruplar karşılaştırıldığında sadece infertilite süreleri arasında istatiksel fark saptandı (p

Anahtar Kelimeler:

Anti-müllerian hormon; over rezervi; infertilite; intrauterin inseminasyon

Antimüllerian Hormon ve İntrauterin İnseminasyon Sikluslarında Ovarian Yanıt: Prospektif Çalışma

Objective: The purpose was to investigate the AMH level and other ovarian reserve markers in the different ovarian response groups. Material and Methods: 80 patients treated with intrauterine insemination were evaluated who were admitted to the Infertility Clinic, Department of Obstetrics and Gynecology of Ege University between September 2009 and May 2011. According to ovarian response each of the groups were divided as less, normal, more ovarian response subgroups and these subgroups were compared for basal AMH, LH, FSH, E2, PRL, age, number of antral follicles and pregnancy. Results: There was found only statistical difference between duration of infertility when Clomiphene citrate and gonadotropin-given groups were According to low, normal and more ovarian response, there was AMH, FSH, LH, antral folliclecount, age, E2 values. The AMH was correlated with antral follicle count (p

Keywords:

Anti-müllerian hormone; ovarian reserve; infertility; intrauterin insemination,

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