Emine DÜNDAR, Gülten ÜNLÜ, Şemsi Nur KARABELA, Kadriye KART YAŞAR

Menenjit Tanılı Hastada Gelişen DRESS Sendromu; Olgu Sunumu

ÖZDRESS (Drug Rash with Eosinophilia and Systemic Sypmtoms) Sendromu, solid organ tutulumu, cilt tututlumu, hematolojik tutulumu yapan ilaç reaksiyonudur. Tedavi edilmezse mortal seyredebilir. En sık sebep olan ilaçlar aromatik antikonvülzanlardır. Biz bu çalışmada nadir görülen menenjit tanılı hastada gelişen DRESS sendromu olgusunu sunduk. Hastalık sistemik tutulum yapması ve mortal seyredebilmesi nedeniyle erken tanı ve tedavi önemlidir.

DRESS Syndrome in Patient with Diagnosis of Meningitis; Case Report

ABSTRACTDRESS (Drug Rash with Eosinophilia and Systemic Sypmtoms) Syndrome, solid organ involvement, skin immunity, hematological involvement is the drug reaction. If not treated, it may be mortal. The most common drugs are aromatic anticonvulsants. In this study, we present a rare case of DRESS syndrome with diagnosis of meningitis. Early diagnosis and treatment are important because of the systemicinvolvement and mortality

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1. Cho YT, Yang CW, Chu CY. Drug reaction with eosinophilia and systemic symptoms (DRESS). Int. J. Mol. Sci. 2017, 18, 1243.
2. De A, Rajagopalan M, Sarda A, et al. Drug reaction with eosinophilia and systemic symptoms. Indian J Dermatol. 2018 Jan-Feb; 63 (1): 30-40.
3. Watanabe H. Recent advances in druginduced hypersensitivity syndrome / drug reaction. Journal of immunology research, volume 2018, article ID 5163129.
4. Oliveira AM, Carvalho R, Martins A, et al. Acute hepatitis in the DRESS syndrome. GE Port J Gastroenterol, 2016; 23 (6): 304-308.
5. Uçal-Bakkal S, Koçak-Tufan Z, Bulut C, et al. A case of DRESS syndrome mimicking sepsis. Klimik Magazine 2011; 24 (2): 132-4.
6. Kizilbash Q, Vasquez A, Seaworth B. Strategies for RIPE. Brief Report, Open forum Infectious Disease.
7. James J, Sammour YM, Virata AR, et al. Drug reaction with eosinophilia and systemic symptoms (DRESS). Am J Case Rep, 2018; 19: 163-170.
8. Wilcox O, Hassanein M, Armstrong J, et al. Case report: atypical presentation of vancomycin BMC Pulmonary Medicine (2017) 17: 217.
9. Leman RE, Chen L, Shi X, et al. Drug reaction with eosinophilia and systemic symptoms (DRESS). JAAD Case Reports 2017; 3: 332-5.
10. Tetik B, Oguzoglu AS, Kayhan-Tetik B, et al. DRESS syndrome after phenytoin use: A case report. Ankara Med J, 2017; (4): 308-13