ZAFER BÜYÜKTERZİ, Mehmet Sertaç APAYDIN, Halil Ekrem AKKURT, HALİM YILMAZ

Epicardial adipose tissue thickness is associated with disease severity in patients with newly- diagnosed ankylosing spondylitis

INTRODUCTION: Cardiovascular (CV) disease is a welldescribed co-morbidity in patients with inflammatory arthritis. Epicardial adipose tissue (EAT) contributes to the development and progression of coronary atherosclerosis independent of traditional CV risk factors. In this study, we aimed to investigate whether EAT thickness determined by transthoracic echocardiography (TTE) in newly-diagnosed ankylosing spondilitis (AS) patients is associated with AS severity. METHODS: In this retrospective study, TTE reports of newlydiagnosed AS patients were reviewed. Age- and gendermatched control subjects who fulfilled the inclusion criteria were also included in the study. RESULTS: 100 subjects [40.00 (34.25- 48.00) years, 65% male] were included in the study. EAT thickness was significantly increased in AS patients when compared to the controls (p

Yeni tanı konulan ankilozan spondilitli hastalarda epikardiyal yağ dokusu kalınlığı hastalık ciddiyeti ile ilişkilisi

GİRİŞ ve AMAÇ: İnflamatuar hastalıklarda kardiyovasküler hastalıkların eşlik ettiği daha önceki çalışmalarda tanımlanmıştır. Geleneksel risk faktörlerinin yanı sıra epikardiyal yağ dokusu koroner ateroskleroz gelişim ve ilerlemesine katkıda bulunur. Bu çalışmada yeni tanı konulan ankilozan spondilitli (AS) hastalarda transtorasik ekokardiyografi ile ölçülen epikardiyal yağ doksu kalınlığı ile hastalık ciddeti arasındaki ilişkiyi araştırmayı amaçladık. YÖNTEM ve GEREÇLER: Bu retrospektif çalışmada yeni tanı konulan ankilozan spondilitli hastaların transtorasik ekokardiyografi raporları tarandı. Ayrıca katılım kriterlerini sağlayan yaş ve cinsiyet eşlenik bireyler control grubu olarak çalışmaya dahil edildi. BULGULAR: 100 birey [40.00 (34.25- 48.00) yıl, 65% erkek] çalışmaya dahil edildi. Epikardiyal yağ dokusu kalınlığı AS’li hastalarda control grubuna göre artmıştı (p

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