İnsülin Direnci İçin Pratik Değerlendirme Yöntemleri ve Yaklaşım

Özİnsülin direnci genel olarak insüline düşük biyolojik yanıt olarak tanımlanabilir. Ancak günümüzde başta, obezite, glukoz intoleransı, diyabet ve polikistik over sendromugibi pek çok hastalığın patogenezinde insülin direncinin yattığı bilinmektedir. İnsülin direncini ölçümlemek için farklı laboratuvar metodları önerilmiş olsa bile halen tanı için tek ve kolay uygulanabilir bir ölçüm yöntemi bulunmamaktadır. Tanı daha çok klinik ve diğer laboratuvar tetkikleri ile konulmaktadır.

Anahtar Kelimeler:

İnsülin direnci, İnsülin, Diabetes mellitus

Practical Approach to Insulin Resistance

AbstractInsulin resistance could be described as, low biological response to a given insulinconcentration. The syndromes of insulin resistance actually make up a broad clinical spectrum, which includes obesity, glucose intolerance, diabetes and metabolic syndrome. Manyof these disorders are associated with various endocrine metabolic and genetic conditions. In clinical practice these is no one single laboratory test is used to diagnose insulin resistance. Diagnosis is based on clinical findings corroborated with laboratory tests.

Keywords:

Insulin resistance, insulin, Diabetes Mellitus,

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