Nondiabetik Kadında Sklerozan Lenfositik Lobulit: Olgu Sunumu

ÖzBenign meme hastalığı sklerozan lenfositik lobulitin otoimmün hastalıklar sonucu ol-duğu düşünülmektedir. 46 yaşında bayan hasta memesinde şişlik şikayeti ile genel cerrahi bölümüne başvurdu. Şişlik, 8x5 cm ölçülerinde ağrılı, şiş ve kızarıktı. Hasta, daha önce hipotroidizm vehepatit B tanısı almıştı. Histopatolojik bulgular perilobüler alanlarda lenfositik inflamasyon, belirgin keloid benzeri stromal skleroz gösterdi. Sklerozan lenfositik lobulit tanısı konuldu.

Anahtar Kelimeler:

Lobulit, otoimmunite, meme

Sclerosing Lymphocytic Lobulitis in Nondiabetic Woman

AbstractThe benign breast disease sclerosing lymphocytic lobulitis is thought to result fromauto immune diseases.46-year-old woman visited department of general surgery complaining of a lump inher breast. It was 8x5 cm in diameter, painful, swelling, reddish.The patient was diagnosed with hypothyroidism and hepatitis B previously. Histopathological findings demonstrated marked keloidlike stromal sclerosis andlymphocyte inflamation in the perilobular areas. Sclerosing lymphocytic lobulitis wasdiagnosed.

Keywords:

lobulitis, autoimmunity, breast,

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Kaynaklar 1.Park SH, Choi SJ, Jung HK. Sclerosing lymphocytic lobulitismanifesting as suspicious microcalcifications with Hashimoto'sthyroiditis in a young woman. Breast J. 2013;19(5):539-41. 2.Schwartz I.S., Strauchen J.A.: Lymphocytic mastopathy. Anautoimmune disease of the breast?. Am J ClinPathol 1990;93:725-730. 3.Lammie GA, Bobrow LG, Staunton MD, Levison DA, Page G,Millis RR. Sclerosing lymphocytic lobulitis of the breast-evi-dence for an autoimmune pathogenesis. Histopathology1991; 19:13-20. 4.Tomaszewski J.E., Brooks J.S., Hicks D., Livolsi V.A.: Dia-betic mastopathy: a distinctive clinicopathologic entity. HumPathol 1992; 23:780-786. 5.Aozasa K, Ohsawa M, Saeki K, Horiuchi K, Kawano K, Ta-guchi T. Malignant lymphoma of the breast. Immunologic typeand association with lymphocytic mastopathy. Am J ClinPat-hol 1992; 97: 699–704. 6.Lee AH, Mills RR, Bobrow LG. Primary lymphoma of the bre-ast and lymphocytic lobulitis. Histopathology 1994; 25:297–298. 7.Rooney N, Snead D, Goodman S, Webb AJ. Primary breastlymphoma with skin involvement arising in lymphocytic lobu-litis. Histopathology 1994; 25: 297–299. 8.Fong D, Lann MA, Finlayson C, Page DL, Singh M. Diabe-tic (lymphocytic) mastopathy with exuberant lymphohistiocy-tic and granulomatous response: a case report with review ofthe literature. Am J SurgPathol 2006; 30:1330-1336. 9.Batrani M, Bhardwaj M, Biswal UC.Sclerosing lymphocyticlobulitis in a male patient with asthma.Breast Dis.2011;33(3):143-7. 10.Boufettal H, Mahdaoui S, Noun M, Hermas S, Samouh N, Be-nayad S, Azzouzi S, Zamiati S. Idiopathic granulomatous mas-titis with favorable outcome with medical treatment. Rev MedInterne. 2011;32(2):26–28. 11.Lütfi Doğan, Niyazi Karaman, Can Atalay.Reaktif ve enfla-matuvar meme tümörleri ve hastalıkları Ulusal Cerrahi Der-gisi.2011;27(3): 182-186.