EFFECTS OF WILLOW BARK Salix alba AND ITS SALICYLATES ON BLOOD COAGULANT

EFFECTS OF WILLOW BARK Salix alba AND ITS SALICYLATES ON BLOOD COAGULANT

The herb white willow Salix alba , also known as willow bark, is used to treat pain and fever. White willow contains a substance salicine that is converted by the body into a salicylate similar to the blood-thinner aspirin. Over the last twenty years, yet another use for aspirin has emerged connected with the discovery of its anti-thrombotic action.

___

  • Aberg, B. 1981. Plant growth regulators. XLI. Monosubstituted benzoic acids. Swedish J. Agric. Res. 11: 93–105.
  • Bergner, P. 2001. Salix: Willow bark and NSAID. Medical Herbalism. Mat. Med. and Phar. 3: 2–7.
  • Blumenthal, M., Busse WR., Goldberg A., Gruenwald, J., Hall, T., Riggins, CW., Rister, RS., eds. Klein S., Rister, RS. 1998. The Complete German Commission E Monographs Therapeutic Guide to Herbal Medicines. Austin, TX: Am. Bot. Coun.. Boston: Integrative Medicine Communication.
  • Bradley, PR. 1992. British Herbal Compendium, vol 1. Bournemouth, Dorset, UK. British Herbal Med. Ass. 224–6.
  • Chrubasik, S., Shvartzman, P. 1999. Rheumatic Pain Treatment With Willow Bark (Salicis Cortex). Coherence, 1. 1/99.
  • Fiebich, BL, Appel K. 2003. Anti-inflammatory effects of willow bark extract. Clin. Phar. Ther. 74: 96.
  • Food and Drug Administration, 2003. HHS: Labeling for oral and rectal over-the-counter drug products containing aspirin and nonaspirin salicylates; Reye’s syndrome warning. Final rule. Fed. Regist. 68: 18861-9.
  • Hathcock, J. 1997. Vitamin and Mineral Safety. Council for Responsible Nutrition:Washington DC. 30-32, 39, 41-46, 49-50.
  • MacLagan, TJ. 1876. The treatment of acute rheumatism by salicin. Lancet. 342-383.
  • Newall, CA., Anderson, LA., Philpson, JD. 1996. Herbal Medicine. A Guide for Healthcare Professionals. London, UK. The Pharmaceutical Press. 296.
  • Quick, AJ. 1966. Salicylates and bleeding: the aspirin tolerance test. Am. J. Med. Sci. 252:265–9.
  • Peirce, A. 1999. The American Pharmaceutical Association practical guide to natural medicines. New York. William Morrow and Company, Inc.
  • Ruggeri, ZM. 2002. Platelets in atherothrombosis. Nat. Med. 8: 1227–34.
  • Schrör, K. 2009. Acetylsalicylic Acid. Weinheim. ISBN: 978–3– 527–32109–4 Copyright. WILEY-VCH Verlag GmbH & Co. KGaA. 29 p.
  • Szczeklik, A., Nizankowski, R., Skawinski, S., Szczeklik, J., Gluszko, P., Gryglewski, RJ. 1979. Successful therapy of advanced arteriosclerosis obliterans with prostacyclin. Lancet, 1:1111-1114.
  • Vlachojannis, J., Magora, F., Chrubasik, S. 2011. Willow Species and Aspirin: Different Mechanism of Actions. Phytotherapy Res., 25: 1102–1104.
  • Weiss, HJ, Aledort, LM. 1967. Impaired platelet-connective- tissue reaction in man after aspirin ingestion. Lancet, 2: 495–7.