Nouria BOUKENAOUI-FERROUK, Elara MOUDILOU, Zaina AMIRAT, Jean-Marie EXBRAYAT, Farida KHAMMAR

Morphometric Study and Immunolocalization of Androgen Receptors in Epididymis During Postnatal Development in D’Man Lamb Reared Under Arid Environment in Algeria

Bu çalışmanın amacı D'Man kuzularında postnatal gelişim süresince epididimiste androjen reseptörlerinin immunolokalizasyonunu ve morfometrisini araştırmaktır. 2 ile 5 ay arasında yaşları değişen kuzulardan kesim sonrasında epididimisler toplandı. Epididymis ağırlığı 3 aylık olanlarda anlamlı oranda farklı bulundu. Corpus ve cauda epididimal tüplerin tubular çapları sırasıyla 2'den 4 aylığa ve 2'den 5 aylığa kadar olanlarda artma gösterdi. Caput epididimal tüplerin luminal çapları 3 aylıklarda anlamlı oranda arttı. Corpus ve cauda epididimal tüplerin luminal çapları sırasıyla 3 ve 4 aylıklarda anlamlı oranda arttı. Caput ve cauda epididimal tüplerin epitel yükseklikleri 5 aylıklarda anlamlı oranda artış gösterdi. Corpus epididimal tüplerin epitel yükseklikleri 3 aylıklarda anlamlı oranda artış gösterdi. Androjen reseptör immunboyanması tüm yaş gruplarında epididimisin epitel hücrelerinin çekirdek ve sitoplazmalarında, düz kas hücrelerinde ve intersitisyel hücrelerinin sitoplazmasında lokalize oldu. Sonuç olarak; morfometrik değişimler ve androjen reseptör immunolokalizasyonu epididimisin postnatal gelişimi ve oluşumu süresince androjenlerin gerekli olduğunu göstermiştir

Cezayir’in Kurak İkliminde Yetiştirilen D’Man Kuzularinda Postnatal Gelişim Süresince Epididimiste Androjen Reseptörlerinin İmmunolokalizasyonu ve Morfometrik Bir Çalışma

The aim of this study was to examine the morphometry and the immunolocalization of androgen receptors in the epididymis of D’Man lamb during postnatal development. The epididymis was collected at the slaughtering lamb, aged of 2 to 5 month. The weight of the epididymis increased with a significant difference at 3 months. The tubular diameter of the corpus and the cauda epididymal tubules increased respectively from 2 till 4 months, and from 2 till 5 months. The luminal diameters of the caput epididymal tubules increased significantly at 3 months. The luminal diameters of the corpus and cauda epididymal tubules increased significantly from 3 and 4 months respectively. The epithelial height of the caput and cauda epididymal tubules increased significatively at 5 months. The epithelial height of the corpus epididymal tubules increased significantly at 3 months. The androgen receptor immunostaining was localized in nuclei and cytoplasm of epithelial cells, smooth muscle cells and in the cytoplasm of interstitial cells of the epididymis at each age. In conclusion, both the morphometric changes and androgen receptors immunolocalization during the postnatal development of epididymis indicated the necessity of androgens for postnatal differentiation and maintaining the structure of the epididymis

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