Mimi RISTEVSKI, Bojan TOHOLJ, Marko CINCOVI?, Plamen TROJA?ANEC, Jo?e STARI?, Ozren SMOLEC

Milk Production, Body Condition Score and Metabolic Parameters at the Peak of Lactation as Risk Factors for Chronic Lameness in Dairy Cows

Bu olgu-kontrol çalışmasının amacı ineklerde laktasyonun pik yaptığı ilk altı ayı süresince kronik topallığın risk faktörleri olarak süt üretimi, vücut kondisyon skoru ve metabolik parametrelerin incelenmesidir. Çalışmada toplam 100 adet Holstein-Friesian inek kullanıldı. Bu ineklerin 30'u topal (5 aylık ölçümlerin 4'üne belirlenen lokomosyon skoru (LS) >3'e göre) olarak sınıflandırılırken 70'i klinik olarak topallık göstermemekteydi (LS 0.8 mmol/L (OR=3.5, CI=1.2-9.9), LDH>1900 IU/L (OR=2.3, CI=1.4-5.9) ve trigliseridler>0.22 mmol/L (OR=2.2, CI=1.5-2.9). İki risk faktörünün etkileşmesi tek faktöre maruz kalanlarla karşılaştırıldığında kronik topallığın gelişmesi için daha yüksek OR gösterdi BCS × BHBA , BCS×LDH , süt üretimi × BHBA ve süt üretimi×LDH . Risk faktörlerine maruz kalan topal inekler muhtemelen enerji ve protein dengesizliğine bağlı olarak anlamsız derece daha düşük üre konsantrasyonuna, ALP ve daha yüksek kolesterol ve trigiliserid konsantrasyonuna sahipti. Topal ve sağlıklı ineklerde glikoz konsantrasyonu benzerlik göstermekteydi. Sağlıklı ineklerde düşük LDH aktivitesi ile birlikte benzer ortalama glikoz konsantrasyonu sağlanırken topal ineklerde artmış LDH mevcuttu. Bu durum muhtemelen yüksek glikolizise bağlıydı. Laktasyonun pik döneminde metabolik adaptasyon ve topallık ile ilişkisi daha fazla çalışmaya ihtiyaç olduğunu göstermektedir

Sütçü İneklerin Laktasyon Pikinde Kronik Topallığın Risk Faktörleri Olarak Süt Üretimi, Vücut Kondisyon Skoru ve Metabolik Parametreler

The objective of this case-control study was to examine the milk production, body condition score and metabolic profiles at the peak of lactation as risk factors for chronic lameness present in cows during the first six months of lactation. A total of 100 Holstein-Friesian cows were enrolled in the study, out of which 30 were classified as lame (a locomotion score (LS) >3 according to 4 of 5 monthly measurements) and 70 exhibited no signs of clinical lameness (LS ≤3). The cows with milk production above 30.9 kg/day showed a higher risk for chronic lameness (OR=1.9, a 95% confidence interval (CI)=1.2-4.5), and the risk peaked at a milk production of 39.1 kg/day (OR=4.8, CI=2.1-8.8). A suboptimal BCS 3 at the peak of lactation increased the probability of lameness in the exposed group of cows . The cows were exposed to higher risk factors for chronic lameness under the following circumstances: BHBA>0.8 mmol/L (OR=3.5, CI=1.2-9.9), LDH>1900 IU/L (OR=2.3, CI=1.4-5.9), and triglycerides>0.22 mmol/L (OR=2.2, CI=1.5-2.9). The interaction between two risk factors showed a higher OR for developing chronic lameness in comparison with a single-factor exposure: BCS × BHBA , BCS×LDH , milk production × BHBA and milk production×LDH . Lameness cows exposed to risk factor showed un-significant lower concentration of urea, ALP and higher concentration of cholesterol and triglycerides probably due to energy and protein malnutrition. Glucose concentrations were similar in healthy and lameness cows. Same mean concentration of glucose was maintained with decrease of LDH activity in healthy cows, but with increase LDH in lame cows, probably due to high glycolysis. Metabolic adaptation in pick of lactation and its relation with lameness need further research

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