Kuzularda Serum ve Kolostral IgG (Pasif İmmünite) Konsantrasyonlarının Total Protein ve Sağlık İle İlişkisi

Bu çalışma kuzulamadan önce koyun serum, kolostrum ve 1. günde kuzularının total protein (TP) ve immunoglobulin-G (IgG) seviyeleri arasındaki ilişkinin ve bu parametlerin neonatal hastalıklar üzerindeki etkisinin ve ayrıca neonatal periyodun farklı günlerinde serum TP ve IgG konsantrasyonları (STPK ve SIgGK) arasındaki linear ilişkinin belirlenmesi, böylece TP konsantrasyonunun pasif immunite ve kolostrumun kalitesinin belirlenmesinde kullanılabilirliğinin belirlenmesi ve doğumdan sonra 24. saat STPK ve SIgGK pasif immunite ve kuzularda hastalık ve ölüm riskini artıran eşik değerinin (STPK-24 ve SIgGK-24, sırasıyla) belirlenmesi için dizayn edildi. Bu amaçla tüm kuzulardan 1. gün (n=325), kolostrum almadan önce (0. saat/gün) ve sonraki günlerde (n=50) ve annelerinden kuzulamadan 10-15 gün önce kan ve ayrıca kolostrum örnekleri alındı. Neonatal periyotta sağlıklı olduğu belirlenen kuzulardan yaşamın 1, 2, 4, 7, 14 ve 28. günlerinde ortalama serum TP ve IgG seviyelerinin 0. güne göre (kolostrum almadan önce) önemli seviyede yüksek olduğu belirlendi. Neonatal dönemde hastalanan ve ölen kuzuların STPC-24’ları sağlıklı olanlara göre önemli seviyede düşük olduğu saptandı (sırasıyla P

Interrelationships of Serum and Colostral IgG (Passive Immunity) with Total Protein Concentrations and Health Status in Lambs

This study was designed to determine relationship between sheep serum before lambing, colostrum and 1-day-old lamb serum total protein (TP) and immunoglobulin-G (IgG) concentration and their effct on neonatal diseases and also the linear relationship between serum TP and IgGconcentration (STPC and SIgGC, respectively) in diffrent days of the neonatal period thereby determining the feasibility of TP concentration in the prediction of colostrum quality and passive immunity and to define a cut-of point for STPC and SIgGCat 24 h after birth (STPC-24 and SIgGC-24, respectively) associated with increased risk of illness or death in lambs. For this purpose, blood was obtained from the lambs and ewes at day 1 (n=325), at day 0 (before colostrum intake) and on diffrent days in neonatal periods (n=50) and blood (10-15 days before lambing) and colostrum were obtained from the respective ewes related to the lambs. Mean serum TP and IgG concentrations on days 1, 2, 4, 7, 14 and 28 were significantly higher than values on day 0 (before colostrum intake) from the lambs remained healthy in neonatal period. The STPC-24 was significantly lower in diseased and dead lambs when compared to healthy lambs in the neonatal period (P

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