Etlik Piliçlerde Pleurotus sajor-caju Sıcak Su ve Metanolik Ekstraktının İmmunolojik ve Anti-Eimeria Etkileri

Bu çalışmada Pleurotus (P.) sajor-caju (yerel yetişen bir istiridye mantarı) sıcak su ve metanolik ekstraktının bağışıklık düzenleyici ve anti-Eimeria etkileri araştırılmıştır. Mantarlardan liyofilizasyonla sıcak su ve metanolik ekstraktı elde edildi. Liyofilize edilen ekstraktlar bağışıklık düzenleyici ve anti-Eimeria aktivitelerini test etmek amacıyla analiz edildi. Ticari broiler tavuklarda bu ekstraktların bağışıklık düzenleyici etkisinin değerlendirilmesi sonucunda kontrol ile karşılaştırıldığında fitohemaglutinine karşı lenfoproliferatif cevap ile karakterize hücre aracılı bağışıklığın anlamlı derecede yüksek olduğu belirlendi (P

Immunological and anti-Eimeria Effects of Hot Water and Methanolic Extracts of Pleurotus sajor-caju in Broiler

Present study reports the immunomodulatory and anti-Eimeria effects of hot water and methanolic extracts of Pleurotus (P.) sajor-caju (alocally grown oyster mushroom). Mushrooms were processed to obtain hot water and methanolic extracts followed by lyophilization. Thelyophilized extracts were subjected to proximate analysis followed by their evaluation for immunomodulatory and anti-Eimeria activities.Immunomodulatory evaluation of these extracts in industrial broilers revealed significantly higher (P

___

  • Ozkan O, Sarı B, Bayezit M, Dogan A, Akpulat HA, Erdag D: Anticoccidiosis effect of Thymus serpyllum in rabbits: Oocyst shedding and body weight changes. Kafkas Univ Vet Fak Derg, 16, 323-327, 2010. DOI: 10.9775/kvfd.2009.790
  • Sarı B, Çakmak A: Preventive effects of anticoccidial drug supplementation in chicken feed against coccidiosis in broiler farming. Kocatepe Vet J, 1, 1-10, 2008.
  • Willis WL, Wall DC, Isikhuemhen OS, Ibrahim S, Minor RC, Jackson J, Hurley SL, Anike F: Effect of different mushrooms fed to Eimeriachallenged broilers on rearing performance. Int J Poult Sci, 11, 433-437, 2012.
  • Dalloul RA, Lillehoj HS, Lee JS, Lee SH, Chung KS: Immunopotentiating effect of a Fomitella fraxinea - derived lectin on chicken immunity and resistance to coccidiosis. Poult Sci, 85, 446-451, 2006. DOI: 10.1093/ps/85.3.446
  • Moradali MF, Mostafavi H, Ghods S, Hedjaroude GA: Immunomodulating and anticancer agents in the realm of macromycetes fungi (macrofungi). Int Immunopharmacol, 7, 701-724, 2007. DOI: 10.1016/j. intimp.2007.01.008
  • Borchers AT, Keen CL, Gershwin ME: Mushrooms, tumors and immunity: An update. Exp Biol Med, 5, 393-406, 2004. DOI: 10.1177/ 153537020422900507
  • Zhang Q, Lin Z: Study on antitumor activity and mechanism of Ganoderma polysaccharides B. Chin J Integ Trad West Med, 19, 544-547, 1999.
  • Girard F, Fort G, Yvore P, Quere P: Kinetics of specific immunoglobulin A, M and G production in the duodenal and caecal mucosa of chicken infected with Eimeria acervulina or Eimeria tenella. Int J Parasitol, 27, 803- 809, 1997. DOI: 10.1016/S0020-7519(97)00044-1
  • Chen HL, Li DF, Chang BY, Gong LM, Piao XS, Yi GF, Zhang JX: Effects of lentinan on broiler splenocytes proliferation, Interleukin-2 production, and signal transduction. Poult Sci, 5, 760-766, 2003. DOI: 10.1093/ps/82.5.760
  • Guo FC, Kwakkel RP, Williams BA, Suo X, Li WK, Verstegen MWA: Coccidiosis immunization: effects of mushroom and herb polysaccharides on immune responses of chickens infected with Eimeria tenella. Avian Dis, 49, 70-73, 2005. DOI: 10.1637/7227-062504R1
  • Guo FC, Kwakkel RP, Williams BA, Parmentier HK, Li WK, Yang ZQ, Verstegen MW: Effects of mushroom and herb polysaccharides on cellular and humoral immune responses of Eimeria tenela-infected chickens. Poult Sci, 83, 1124-1132, 2004. DOI: 10.1093/ps/83.7.1124
  • Liang JL, Hu TJ, Fan BT: Experiment of 8301 polysaccharide including IFN production in rats. J Trad Chin Vet Med, 4, 12-13, 1995.
  • Liu JJ, Huang TS, Hsu ML, Chen CC, Lin WS, Lu FJ, Chang WH: Antitumor effects of the partially purified polysaccharides from Antrodia camphorate and the mechanism of its action. Toxicol Appl Pharmacol, 201, 186-193, 2004. DOI: 10.1016/j.taap.2004.05.016
  • Wei P, Li QZ, Hao YH: Effect of Astragalus mongholicus Bga and Lentinus edodes polysaccharide on Lipid peroxide (LPO) content in VMDV infected chicks. J Trad Chin Vet Med, 4, 3-4, 1997
  • Awais MM, Akhtar M, Iqbal Z, Muhammad F: Saccharum officinarum derived high molecular mass glycoproteins as native biological response modifiers in chickens. Pak Vet J, 34, 464-468, 2014.
  • She QB, Ng TB, Liu WK: A novel lectin potent immunomodulatory activity isolated from both fruiting bodies and cultured mycelia of the edible mushroom Volvariella volvacea. Biochem Biophys Res Commun, 247, 106-111, 1998. DOI: 10.1006/bbrc.1998.8744
  • Reis FS, Barros L, Martins A, Ferreira ICFR: Chemical composition and nutritional value of the most widely appreciated cultivated mushrooms: An inter-species comparative study. Food Chem Toxicol, 50, 191-197, 2012. DOI: 10.1016/j.fct.2011.10.056
  • Shamtsyan M, Konusova V, Maksimova Y, Goloshchev A, Panchenko A, Simbirtsev A, Petrishchev N, Denisova N: Immunomodulating and anti-tumor action of extracts of several mushrooms. J Biotechnol, 113, 77- 83, 2004. DOI: 10.1016/j.jbiotec.2004.04.034
  • Manzi P, Gambelli L, Marconi S, Vivanti V, Pizzoferrato L: Nutrients in edible mushrooms: An inter-species comparative study. Food Chem, 65, 477-482, 1999. DOI: 10.1016/S0308-8146(98)00212-X
  • Ouzouni PK, Veltsistas PG, Paleologos EK, Riganakos KA: Determination of meat content in wild edible mushroom species from regions of Greece. J Food Compost Anal, 20, 480-486, 2007. DOI: 10.1016/j. jfca.2007.02.008
  • Patel Y, Naraian R, Singh VK: Medicinal properties of Pleurotus species (oyster mushroom): A review. World J Fungal Plant Biol, 3, 1-12, 2012.
  • Burgh M: A Simple method for recording and analyzing serological data. Avian Dis, 22, 362-365, 1978. DOI: 10.2307/1589552
  • Guven E, Avcioglu H, Aslan A, Hayirli A: Anticoccidal efficacy of usnic acid in broilers. Kafkas Univ Vet Fak Derg, 22 (4): 551-556, 2016. DOI: 10.9775/kvfd.2016.15008
  • Ryley JF, Meade R, Hazelhurst J, Robinson TE: Methods in coccidosis research: Separation of oocysts from faeces. Parasitol, 73, 311-326, 1976. DOI: 10.1017/S0031182000046990
  • Khaliq K, Akhtar M, Awais MM, Anwar MI: Evaluation of immunotherapeutic effects of Aloe vera polysaccharides against coccidiosis in chicken. Kafkas Univ Vet Fak Derg, 23 (6): 895-901, 2017. DOI: 10.9775/ kvfd.2017.17957
  • Awais MM, Akhtar M, Anwar MI, Khaliq K: Evaluation of Saccharum officinarum L. bagasse-derived polysaccharides as native immunomodulatory and anticoccidial agents in broilers. Vet Parasitol, 249, 74-81, 2018. DOI: 10.1016/j.vetpar.2017.11.012
  • Ahmad I, Hussain M, Ahmad MSA, Hameed M, Ashraf MY, Shinwari ZK, Nawaz T, Batool R, Fatima S: Spatio-temporal variations in some medicinally important biochemical constituents of Peganum harmala (hermal). Pak J Bot, 45, 601-607, 2013.
  • Yang JH, Lin HC, Mau JL: Antioxidant properties of several commercial mushrooms. Food Chem, 77, 229-235, 2002. DOI: 10.1016/ S0308-8146(01)00342-9
  • Han SSR, Cho CK, Lee YW, Yoo HS: Antimetastatic and immunomodulating effect of water extracts from various mushrooms. J Acupunct Meridian Stud, 2, 218-227, 2009. DOI: 10.1016/S2005-2901(09)60058-3
  • Kaneno R, Fontanari LM, Santos SA, Di Stasi LC, Rodrigues FE, Eira AF: Effects of extracts from Brazillian sun- mushroom (Agaricus blazei) on the NK activity and lymphoproliferative responsiveness of Ehrlich tumorbearing mice. Food Chem Toxicol, 42, 909-916, 2004. DOI: 10.1016/j. fct.2004.01.014
  • Sarangi I, Ghosh D, Bhutia SK, Mallick SK, Maiti TK: Anti-tumor and immunomodulating effects of Pleurotus ostreatus mycelia-derived proteoglycans. Int Immunopharmacol, 6, 1287-1297, 2006. DOI: 10.1016/j. intimp.2006.04.002
  • Schepetkin, IA, Quinn MT: Botanical polysaccharides: Macrophage immunomodulation and therapeutic potential. Int Immunopharmacol, 6, 317-333, 2006. DOI: 10.1016/j.intimp.2005.10.005
  • Inacio FD, Ferreira RO, de Araujo CAV, Brugnari T, Castoldi R, Peralta RM, de Souza CGM: Proteases of wood rot fungi with emphasis on the genus Pleurotus. BioMed Res Int, 2015:290161, 2015. DOI: 10.1155/ 2015/290161
  • Zhang M, Cui SW, Cheung PCK, Wang Q: Antitumor polysaccharides from mushroom:a review on their isolation, process, structural characteristics and antitumour activity. Trends Food Sci Technol, 18, 4-19, 2007. DOI: 10.1016/j.tifs.2006.07.013
  • Ullah MI, Akhtar M, Awais MM, Anwar MI, Khaliq K: Evaluation of immunostimulatory and immunotherapeutic effects of tropical mushroom (Lentinus edodes) against eimeriasis in chicken. Trop Anim Health Prod, 50, 97-104, 2018. DOI: 10.1007/s11250-017-1407-4
  • Lin KI, Kao YY, Kuo HK, Yang WB, Chou A, Lin HH, Alice LY, Wong CH: Reishi polysaccharides induce immunoglobulin production through the TLR4/TLR2-mediated induction of transcription factor Blimp-1. J Biol Chem, 281, 24111-24123, 2006. DOI: 10.1074/jbc.M601106200
  • Shao BM, Dai H, Xu W, Lin ZB, Gao XM: Immune receptors for polysaccharides from Ganoderma lucidum. Biochem Biophys Res Commun, 323, 133-141, 2004. DOI: 10.1016/j.bbrc.2004.08.069
  • Heleno SA, Barros L, Sousa MJ, Martin A, Ferreira ICFR: Study and characterization of selected nutrients in wild mushrooms from Portugal by gas chromatography and high performance liquid chromatography. Microchem J, 93, 195-199, 2009. DOI: 10.1016/j.microc.2009.07.002
  • Carbonero ER, Ruthes AC, Freitas CS, Utrilla P, Galvez J, da Silva EV, Sassaki GL, Gorin PAJ, Iacomini M: Chemical and biological properties of a highly branched β-glucan from edible mushroom Pleurotus sajor-caju. Carbohydr Polym, 90, 814-819, 2012. DOI: 10.1016/j.carbpol.2012.06.005
  • Wasser SP: Current findings, future trends, and unsolved problems in studies of medicinal mushrooms. Appl Microbiol Biotechnol, 89, 1323- 1332, 2011. DOI: 10.1007/s00253-010-3067-4
  • Gonzaga MLC, Ricardo NMPS, Heatley F, Soares SA: Isolation and characterization of polysaccharides from Agaricus blazei Murill. Carbohydr Polym, 60, 43-49, 2005. DOI: 10.1016/J.CARBPOL.2004.11.022
  • Grujic M, Dojnov B, Potocnik I, Duduk B, Vujcic Z: Spent mushroom compost as substrate for the production of industrially important hydrolytic enzymes by fungi Trichoderma spp. and Aspergillus niger in solid state fermentation. Int Biodeterior Biodegradation, 104, 290-298, 2015. DOI: 10.1016/j.ibiod.2015.04.029
  • Correa RCG, Brugnari T, Bracht A, Peralta RM, Ferreira ICFC: Biotechnological, nutritional and therapeutic uses of Pleurotus spp. (Oyster mushroom) related with its chemical composition: A review on the past decade findings. Trends Food Sci Technol, 50, 103-117, 2016. DOI: 10.1016/j.tifs.2016.01.012
  • Valverde ME, Hernández-Pérez T, Paredes-López O: Edible mushrooms: Improving human health and promoting quality life. Int J Microbiol, 2015:376387, 2015. DOI: 10.1155/2015/376387
Kafkas Üniversitesi Veteriner Fakültesi Dergisi-Cover
  • ISSN: 1300-6045
  • Yayın Aralığı: Yılda 6 Sayı
  • Başlangıç: 1995
  • Yayıncı: Kafkas Üniv. Veteriner Fak.
Sayıdaki Diğer Makaleler

Identification and Genetic Characterization of Astrovirus in Wild Boar (Sus scrofa) in China

Fan-fan ZHANG, Yu-xin TANG, Yu YE, Nannan GUO, Min ZHANG, Hao LI, Dan LEI, Qiong WU, Dong-yan HUANG, De-ping SONG

Çin’de Yaban Domuzunda (Sus scrofa) Astrovirusların Tanımlanması ve Genetik Karakterizasyonu

Min ZHANG, Yu YE, Qiong WU, Fan-fan ZHANG, Yu-xin TANG, Nannan GUO, Dan LEI, Dong-yan HUANG, De-ping SONG, Hao LI

Effect of Cholesterol and 7-Dehydrocholesterol on Bull Semen Freezing with Different Rates of Glycerol

MUHAMMED ENES İNANÇ, Kemal Tuna OLĞAÇ, Koray TEKİN, Havva ALEMDAR, DOĞUKAN ÖZEN, Ongun UYSAL

Enterotoxemia Caused by Clostridium perfringens Type E in a Calf

Yesari ERÖKSÜZ, Barış OTLU, MEHMET ÇALICIOĞLU, HATİCE ERÖKSÜZ, Canan AKDENİZ İNCİLİ, BURAK KARABULUT, HASAN ABAYLI

Comparison of Oxidative/Nitrosative Stress, Leptin and Progesterone Concentrations in Pregnant and Non-pregnant Abaza Goats Synchronized with Controlled Internal Drug Release Application

MUSHAP KURU, METİN ÖĞÜN, RECAİ KULAKSIZ, ABDULSAMED KÜKÜRT, Hasan ORAL

Utility of Transesophageal Echocardiography in the Diagnosis of Tetralogy of Fallot in a Dog (Bir Köpekte Fallot Tetralojisinin Tanısında Transözefagal Ekokardiyografinin Yararlılığı)

ZEKİ YILMAZ, Meriç KOCATÜRK, Pınar LEVENT, AHMET SARIL, HAKAN SALCI, Saim SAĞ

Evaluation of Genotoxic Effects of C60 Fullerene-γ-Fe2O3 and MultiWall Carbon Nanotubes-γ-Fe2O3 Nanoparticles

ÖZLEM DEMİRCİ TURGUNBAYER, NESRİN HAŞİMİ, ERSİN KILINÇ, VEYSEL TOLAN

Kolombiya, Cordoba’daki Köpeklerde Babesia spp.

Jorge MIRANDA, Salim MATTAR, Carmen GALVÁN, Juan BALLUT

Effect of Thyme Species Extracts on Performance, Intestinal Morphometry, Nutrient Digestibility and Immune Response of Broilers

Mohammad MALEKZADEH, Mir Daryoush SHAKOURI, Hossein ABDI BENAMAR

An Evaluation of the Internal Service Regulation of the Mülki Tatbikat-ı Baytariyye Mektebi (Muavin Baytar Mektebi)

Savaş Volkan GENÇ, Seda TAN