İbrahim Can AYIK, Vermi DEĞERLİ, Gökhan YILMAZ, Emre SEVİM

Laktat Seviyesinin Üst Gastrointestinal Sistem Kanamalı Hastalarda Prognostik Amaçlı Kullanımı

Amaç: Üst GİS kanamalı hastaların risk sınıflandırılmasında en çok Glasgow Blatchford Skoru (GBS) ve Rockall Skoru kullanılmaktadır.Bu skorlama sistemlerinin hiçbirinde serum laktat seviyesi kullanılmamaktadır. Laktat seviyesi travma ve sepsis dahil çeşitli şok durumlarında mortalite beliryecisidir. Çalışmamızın amacı üst GİS kanamalı hastalarda serum laktat seviyesinin prognostik amaçlı kullanımını araştırmaktır. Materyal ve Metot: 1 Mayıs 2015 ve 31 Mayıs 2016 tarihleri arasında, üst gastrointestinal sistem (GİS) kanaması tanısı konmuş 18 yaş ve üstü hastalar çalışmaya alındı. Hastaların yaş, cinsiyet, acil servis kabulündeki hemoglobin ve laktat değeri, kan transfüzyon ihtiyacı, kronik hastalıkları ve GBS değerleri veri formuna kaydedildi. Kan transfüzyon ve yoğun bakım ihtiyacı ile laktat düzeyi arasındaki ilişki araştırıldı. Değişkenlerin analizinde SPSS 22.0 (IBM Corparation, Armonk, New York, United States) programı kullanıldı. Bulgular: Çalışmaya 78 hasta dahil edildi. Hastaların 27’si (%34,6) kadın, 51’i (65,4) erkekti. Yaş ortalaması 67,6±17,75 (min: 22, max: 100) olarak saptandı. Kan transfüzyonu yapılan hastaların median laktat değeri 2,2 mmol/L, kan transfüzyonu yapılmayan hastaların median laktat değeri 1,9 mmol/L olarak bulundu. Bu fark istatiksel olarak anlamlı bulunmadı (p=0,450). Servise yatan hastaların median laktat değeri 1,9 mmol/L, yoğun bakıma yatan hastaların median laktat değeri 3,9 mmol/L bulundu. Bu iki grup arasındaki fark istatiksel olarak anlamlı bulundu (p=0,038). Sonuç: Üst GİS kanamalı hastalarda yoğun bakım ve servis yatışları ile laktat düzeyi arasında anlamlı ilişki saptanmışken; kan transfüzyonu alan ve almayan hastalar arasında laktat düzeyi açısından anlamlı bir ilişki saptanmamıştır

Anahtar Kelimeler:

laktat; gastrointestinal; kanama; kan transfüzyonu; yoğun bakım

Prognostic Usage of Lactate Levels in Patients with Upper Gastrointestinal Bleeding

Aim: Glasgow Blatchford Score (GBS) and Rockall score is the most widely used scoring system for risk classification of patients with upper gastrointestinal bleeding. Lactate levels is not used by any of those scoring systems. Lactate levels is a determinant factor in a variety of conditions including shock, trauma and sepsis. The aim of our study was to investigate prognostic value of serum lactate levels in patients who have GI bleeding. Material and Method: Patients with the age 18 and older who were diagnosed upper gastrointestinal system bleeding, between May 1, 2015 and May 31, 2016, were enrolled in the study. The age, sex, hemoglobin and lactate values in emergency admission, the need for blood transfusion, chronic disease and GBS values were recorded in the data sheet. We investigated the association between blood transfusion and intensive care with lactate level. SPSS 22.0 (IBM Corporation, Armonk, New York, United States) program was used to analyze the variables. Results: 78 patients were included in the study. 27 patients (34.6%) were female and 51 (65.4) were male. The mean age was 67.6±17.75 (min: 22, max: 100). The median lactate levels were 2.2 mmol/L for patients who need blood transfusion and 1.9 mmol/L for patients who who didn’t need. . This difference was not statistically significant (p=0.450). The median lactate levels were 3.9 mmol/L for patients who hospitalized in intensive care and 1.9 mmol/L for patients who did not need intensive care. This difference was statistically significant (p=0.038). Conclusion: In our study, significant relationship between intensive care hospitalization and lactate levels was found; but between the need for blood transfusion and lactate levels we didn’t find a significant relationship

Keywords:

lactate; gastrointestinal; bleeding; blood transfusion; intensive care,

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