Neetu BENNY, Basavana GOWDAPPA, Dushad RAM

Relationship between depression literacy and medication adherence in patients with depression

Objective: To find out the relationship between depression literacy and adherence to medications in subjects with major depressive disorder in remission. Methods: In this cross-sectional hospital-based study, 130 subjects with major depressive disorder were assessed by using socio-demographic data form and clinical proforma designed for this study, Depression Literacy Questionnaire and Medication Adherence Rating Scale. Results: Median scores on D-Lit and MARS were 13.2 and 0.00 respectively. Two patterns of common incorrect responses were regarding the cognitive and treatment aspect of depression. Female gender had statistically significant higher D-Lit score (p=0.025) than male, and Score on D-Lit had statistically significant negative predictive value of score on MARS (R2 =0.059, df=5, F=1.55, p=0.020). Conclusion: Cognitive and treatment aspect of depression literacy is lower in patients with depression in India. Depression literacy is more in women and positively associated with medication adherence

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1. Murray CJ, Lopez AD. Alternative projections of mortality and disability by cause 1990-2020: Global Burden of Disease Study. Lancet. 1997;349:1498-504.
2. Mathers CD, Loncar D. Projections of global mortality and burden of disease from 2002 to 2030. PLoS Med. 2006;3:e442.
3. WHO. Cross-national comparisons of the prevalence and correlates of mental disorders. WHO international Consortium in Psychiatric Epidemiology. Bull World Health Organ. 2000;78:413- 26.
4. Blumenthal R, Endicott J. Barriers to seeking treatment for major depression. Depress Anxiety. 1996-1997;4:273-8.
5. Banerjee S, Varma RP. Factors affecting non-adherence among patients diagnosed with unipolar depression in a psychiatric department of a tertiary hospital in Kolkata, India. Depression Res Treat. 2013;201:1-12.
6. Alekhya P, Sriharsha M, Priya Darsini T, Reddy SK, Venkata Ramudu R, Shivanandh B. Treatment and Disease Related Factors Affecting Non-adherence among Patients on Long Term Therapy of Antidepressants. J Depress Anxiety. 2015;4:2.
7. Gabriel A, Violato C. Depression literacy among patients and public: A literature review. Primary Psychiatry. 2010;17:55-64.
8. Wang J, Adair C, Fick G, Lai D, Evans B, Perry BW, et al. Depression literacy in Alberta: findings from a general population sample. Can J Psychiatry. 2007;52:442-9.
9. Deen TL, Bridges AJ. Depression literacy: rates and relation to perceived need and mental health service utilization in a rural American sample. Rural Remote Health. 2011;11:1803.
10. Bonabi H, Müller M, Ajdacic-Gross V, Eisele J, Rodgers S, Seifritz E, et al. Mental health literacy, attitudes to help seeking, and perceived need as predictors of mental health service use: a longitudinal study. J Nerv Ment Dis. 2016;204:321-4.
11. Ogorchukwu JM, Sekaran VC, Nair S, Ashok L. Mental health literacy among late adolescents in South India: What they know and what attitudes drive them. Indian J Psychol Med. 2016;38:234- 41.
12. Sameed S, Karkal R, Mendonsa R, Shriyan S, Thomas AM, Chandran VM. Help-seeking attitudes for depression among first year medical undergraduates. Indian J Basic Applied Med Res. 2016;5:839-44.
13. Nigam T, Pole R, Vankar GK. Depression literacy among high school adolescents. Archives of Indian Psychiatry. 2013;15:37-41.
14. Griffiths KM, Christensen H, Jorm AF, Evans K, Groves C. Effect of web-based depression literacy and cognitive-behavioural therapy interventions on stigmatising attitudes to depression: randomized controlled trial. Br J Psychiatry. 2004;185:342-9.
15. Morisky DE, Green LW, Levine DM. Concurrent and predictive validity of a self-reported measure of medication adherence. Med Care. 1986;24:67-74.
16. Poongothai S, Pradeepa R, Ganesan A, Mohan V. Prevalence of depression in a large urban South Indian Population - the Chennai Urban Rural Epidemiology Study (CURES - 70). PLoS One. 2009;4(9):e7185.
17. Mantle F. Developing a culture-specific tool to assess postnatal depression in the Indian community. Br J Community Nurs. 2003;8:176-80.
18. Raguram R, Weiss MG, Keval H, Channabasavanna SM. Cultural dimensions of clinical depression in Bangalore, India. Anthro Med. 2000;8:31-46.
19. Gaiha SM, Sunil GA, Kumar R, Menon S. Enhancing mental health literacy in India to reduce stigma: the fountainhead to improve help-seeking behaviour. J Public Ment Health 2014;13:146-58.
20. WHO. Report submitted by South East Asian Office (WHO) on Conquering Depression: You can get out of the blues. 2011.
21. Khan TM, Sulaiman SA, Hassali MA, Anwar M, Wasif G, Khan AH. Community knowledge, attitudes, and beliefs towards depression in the state of Penang, Malaysia. Community Ment Health J. 2010;46:87-92.
22. Darraj HA, Mahfouz MS, Al Sanosi RM, Badedi M, Sabai A, Al Refaei A, et al. Arabic Translation and Psychometric Evaluation of the Depression Literacy Questionnaire among Adolescents. Psychiatry J. 2016;2016:8045262.
23. Highet NJ, Hickie IB, Davenport TA. Monitoring awareness of and attitudes to depression in Australia. Med J Aust. 2002;176(Suppl):S63-8.
24. Oliffe JL, Hannan-Leith MN, Ogrodniczuk JS, Black N, Mackenzie CS, Lohan M, et al. Men's depression and suicide literacy: a nationally representative Canadian survey. J Ment Health. 2016:1- 7.
25. Swami V. Mental health literacy of depression: gender differences and attitudinal antecedents in a representative British sample. PLoS One. 2012;7:e49779.
26. Savas HA, Unal A, Virit O. Treatment adherence in bipolar disorder. JMOOD. 2011;1:95-102.
27. Johnson FR, Ozdemir S, Manjunath R, Hauber AB, Burch SP, Thompson TR. Factors that affect adherence to bipolar disorder treatments: a stated-preference approach. Med Care. 2007;45:545- 52.
28. Johnson A. Health literacy, does it make a difference? Australian Journal of Advanced Nursing. 2014;31:39-45.
29. Azocar F, Branstrom RB. Use of depression education materials to improve treatment compliance of primary care patients. J Behav Health Serv Res. 2006;33:347-53.