Gizem TUTKUN, Ahmet Ozan ÖZGEN, Uğur BİLGE

Olası terapötikler için SARS-CoV-2’nin spike, zarf ve membran proteinlerinin modelleri

Amaç: Şiddetli akut solunum sendromu ile ilişkili SARS-CoV-2, yüksek morbidite ve mortaliteye sahip, yaygın, hızla büyüyen bir enfeksiyon hastalığıdır. Bu virüsün üç yapısal proteininin dizisindeki mutasyonlar, pandeminin ilerlemesi üzerinde önemli bir etkiye sahip olabilir.

Anahtar Kelimeler:

R programlama dili, SARS-CoV-2, Dizi Hizalama, Yapı Proteinleri, Moleküler Modelleme

Models of spike, envelope and membrane proteins of SARS-CoV-2 variants for possible therapeutics

Background: SARS-CoV-2 associated with severe acute respiratory syndrome is a common, rapidly growing infectious disease with high morbidity and mortality. Mutations in the sequence of the three structural proteins of this virus may have a significant impact on the progression of the pandemic.

Keywords:

R programming language, SARS-CoV-2, Sequence alignment, Structural proteins, Molecular modelling,

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