Mehmet AYDİN, Mustafa Can GÜLER, Canan ATALAY, Osman Nuri KELEŞ

X-Ray Cihazına Benzeyen Kan-Beyin Bariyerlerinin Çalışma Prensiplerini Açıklamaya Doğru: Bir Nörofizik Hipotez

Amaç: Kan-beyin bariyeri, nörofiziksel temelde elektromanyetik bir mekanizmadır. Bu çalışmada kan-beyin bariyerini, ona birçok yönden benzeyen X-Ray cihazı ile karşılaştırdık. Gereç ve Yöntem: On sıçanın derin temporal korteks bölümlerinden beyin örnekleri topladık. Daha sonra glial fibriler asidik protein (GFAP) tekniği ile boyadık. Akabinde kan-beyin bariyerlerinin mimari yapılarını görselleştirdik ve X-ray cihazlarıyla karşılaştırdık. Bulgular: X-ray cihazında tüp kan-beyin bariyerini oluşturan arterioller ile elektrik akımını sağlayan ve akımın yönünü belirleyen anot-katot; damarları çevreleyen astrositlere, damarlar için soğutma sistemi örevi gören beyin omurilik sıvısına ve katottan damarda akan parçacıklara yayılan elektronlara karşılık gelir. Sonuç: Kan-beyin bariyerinin sunduğu mimari yapısı sayesinde yolcu bagajındaki nesneleri görüntüleyen ve barkod numaralarına göre yönlendiren bir X-Ray ve optik okuyucu olarak işlev gördüğünü düşünüyoruz.

Anahtar Kelimeler:

Astrosit, Kan-beyin bariyeri, Glial fibriler asidik protein tekniği, Sıçan, X-ray cihazı

Toward to Explain of Working Principles of Blood-Brain Barriers Like X-Ray Devices: A Neurophysical Hypothesis

Objective: The blood-brain barrier is an electromagnetic mechanism on a neurophysical basis. In this study, we compared the X-Ray device, which is similar to the blood-brain barrier in many ways. Material and Methods: We collected brain samples from deep temporal cortex sections of ten rats, stained them via the glial fibrillary acidic protein (GFAP) technique, visualized the architectural structures of the blood-brain barriers, and compared them with X-ray devices. Results: With the arterioles forming the tube blood-brain barrier in the X-ray device, the anode-cathode that provides the electric current and determines the direction of the current flow corresponds to the astrocytes surrounding the anode-cathode vessel, the cooling system to the cerebrospinal fluid circulating the vessel, and the electrons emitted from the cathode to the particles flowing in the vessel. Conclusion: With the architecture presented by the blood-brain barrier, we envision it functioning as an X-Ray and optical reader that display objects in passenger baggage and direct them according to barcode numbers.

Keywords:

Astrocyte, Blood-brain barrier, Glial fibrillary acidic protein technique, Rat, X-ray devices,

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