N-asetil sistein: İlaca bağlı akut pankreatitte de kullanılabilecek bir tedavi seçeneği mi?

Amaç: Akut pankreatit etiyolojisinde ilaçlar nispeten seyrek bir nedendir. Çalışmamızda ilaç kullanımına bağlı akut pankreatit gelişen ve N-asetilsistein tedavisi sonrası iyileşen 6 hastanın retrospektif değerlendirmesini amaçlanmıştır.Gereç ve Yöntem: 2007-2017 yılları arasında ilaca bağlı akut pankreatit tanısı alan ve NAC tedavisi uygulanan 6 çocuk hastanın dosyaları retrospektif olarak incelendi. Altı hastanın akut pankreatit tanısı "Uluslararası Çocuk Pankreatit Çalışma Grubu" tarafından önerilen kriterlere göre konuldu. Hastalığın şiddet derecesi NASPGHAN kriterlerine göre belirlendi. Bulgular: Akut pankreatit tedavisi sırasında NAC uygulanan ilaca bağlı akut pankreatitli 6 hastanın tümü tamamen iyileşti. Sonuç: NAC, ilaca bağlı akut pankreatit tedavisi için faydalı görünmektedir.

Anahtar Kelimeler:

Pankreatit, N-asetil sistein

N-acetyl cysteine: Is it an option for treatment of drug induced acute pancreatitis?

AbstractAim: Drugs are a relatively rare cause of acute pancreatitis. We aimed a retrospective evaluation of 6 patients with drug induced acute pancreatitis, who were recovered after N-acetyl cysteine treatment.Materials and Methods: . The information in the files of 6 patients with drug induced acute pancreatitis who were improved after NAC treatment between 2007 and 2017 was retrospectively reviewed. The criteria recommended by the International Study Group of Pediatric Pancreatitis were used for the diagnosis of acute pancreatitis in 6 patients. The severity of the disease was determined according to NASPGHAN criteriaResults: All of the 6 patients with drug induced acute pancreatitis who underwent NAC during the treatment of acute pancreatitis were completely healed. Conclusion: NAC treatment seems to be beneficial for drug induced acute pancreatitis.

Keywords:

Panceatitis, N-acetyl cysteine,

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