Perihan ÖZKAN GÜMÜŞKAYA, Özgür ALTUN, Nur KARAKÜTÜK YÜZTAŞ, Neslihan ÖZSOY, Gülten AYDIN TUTAK, Emine YILDIRIM, Mine ADAŞ, Mehmet KÜÇÜK

COVID-19 Pnömonisi Sonrası AntiHBs Değerlerindeki Değişiklikler

Amaç: Coronavirus-19 hastalığı (COVID-19) sırasında antiHBS titresinin koruyucu değerin altına düşüp düşmediğini belirlemeyi amaçladık. Gereç ve Yöntem: Son 1 yıl içinde pozitif antiHbs değerleri kontrol edilen 67 hasta ile prospektif bir çalışma yapıldı. Demografik veriler ve önceki antiHBs değerleri hasta dosyalarından toplandı ve COVID-19 enfeksiyonundan bir ay sonra kontrol edilen yeni antiHBs titrelerinin laboratuvar bulguları öncekilerle karşılaştırıldı. Bulgular: COVID-19 sonrası yapılan değerlendirmede COVID-19 hastalarının antiHBs düzeylerinde COVID-19 enfeksiyonu öncesi önceki değerlere göre istatistiksel olarak anlamlı düşüş saptandı(p<0,001). Sonuç: Çalışmamızda COVID-19 enfeksiyonu sonrası AntiHBs düzeylerinde istatistiksel olarak anlamlı bir düşüş olduğunu ancak bunun koruyucu antiHBs düzeyinin altında olmadığını gördük. Sonuç olarak COVID-19 enfeksiyonu sırasında veya sonrasında hepatit B'ye karşı güçlendirici aşıya gerek olmadığını söyleyebiliriz ancak hasta sayısı daha yüksek olan çalışmalarla desteklenmesi uygun olur.

Anahtar Kelimeler:

COVID-19, antiHBs değerleri, değişen titreler.

The Changes In The AntiHBs Values Following COVID-19 Pneumonia

Background/aim: We aimed to determine if there is a decrease in antiHBS titer below the protective value during Coronavirus-19 disease (COVID-19). Materials and methods: A prospective study was made of 67 patients who had positive antiHbs values checked in the last 1 year. Demographic data and the previous antiHBs values were collected from the patient files and the laboratory findings of new antiHBs titers checked after one months later following COVID-19 infection were compared with the previous ones. Results: In the postcovid evaluation, a statistically significant decrease in the antiHBs levels of COVID-19 patients was determined with respect to previous values before COVID-19 infection (p<0,001). Conclusion: In our study, we found that there was a statistically significant decrease in AntiHBs levels after COVID-19 infection, but none of them were below protective antiHBs levels. As a result, we can say a booster vaccination against hepatitis B is not needed during or after COVID-19 infection, but it would be appropriate to support it with studies with a higher number of patients.

Keywords:

COVID-19, antiHBs values, changing titers.,

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