Bilateral over kitlesi: Primer over tümörü? Krukenberg tümörü?
Krukenberg tümörü overin metastatik tümörüdür. Primer malignite odağı en sık mide olmakla beraber meme, safra kesesi, kolon ve pankreas kanseri de overe metastaz yapabilmektedir. Over metastazı oldukça nadir olarak görülmektedir. Primer malignite odağı bilinmeyen hastalarda over metastazlarını primer over kitlelerinden ayırtedebilmek her zaman mümkün olamamaktadır. Bizim olgumuzda primer over kitlesi düşünülerek cerrahi planlanan, krukenberg tümörlü hastanın manyetik rezonans görüntüleme (MRG) bulguları sunulmuştur. Hastaya MRG ile konulan metastatik over tümörü tanısı sonrasında yapılan endoskopisinde midenin taşlı yüzük hücreli kanseri olduğu anlaşılmıştır.
Bilateral ovarian mass: Primary ovarian tumor? Krukenberg tumor?
Krukenberg tumour is a ovarian metastatic tumor. Its most frequently seen primary malignancy focus is stomach and breast, gallblader, colon and pancreas cancers can metastasize, too. Ovarian metastasis is seen very rarely. In patients whose primary malignancy focus is not known, it is not always possible to distinguish ovarian metastasis from ovarian masses. Magnetic resonance imaging (MRI) findings of the patient who had krukenberg tumor and for whom surgical intervention was planned due to the primary ovarian mass are presented in our case. It was seen in the result of the endoscopy applied after metastatic ovarian tumor diagnosis done by MRI that there was signet ring cell carcinoma in the stomach.
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- Kong X, Wang JL, Chen HM, Fang JY. Comparison of the clinicopathological characteristics of young and elderly patients with gastric carcinoma: a meta analysis. J Surg Oncol 2012; 106: 346-52.
- Ummugul Uyeturk, Serife Hulya Arslan, Oznur Bal, Ulku Yalcintas Arslan, Omur Berna Cakmak Oksuzoglu. Isolated ovarian metastasis of gastric cancer: Krukenberg tumor Contemp Oncol (Pozn) 2013; 17 (6): 515–519 DOI: 10.5114/wo.2013.37542.
- Fazzari C, Fedele F, Pizzi G, Crisafulli C. Krukenberg tumour of the ovary: A case report with light microscopy, immunohistochemistry and electron microscopy study. Anticancer Res 2008;28:1417-2057-65.
- Al-Agha O, Nicastri A. An in-depth look at Krukenberg tumor. Arch Pathol Lab Med 2006;130:1725-30.
- Kakushima N, Kamoshida T, Hirai S, Hotta S, Hirayama T, Yamada J, et al. Early gastric cancer with Krukenberg tumor and review of cases of intramucosal gastric cancers with Krukenberg tumor. J Gastroenterol 2003;38:1176-80.
- Kim NK, Kim HK, Park BJ, Kim MS, Kim YI, Heo DS, et al. Risk factors for ovarian metastases following curative resection of gastric adenocarcinoma. Cancer 1999;85:1490-9.
- Benaaboud I, Ghazli M, Kerroumi M, Mansouri A. Krukenberg tumor: 9 cases report. J Gynecol Obstet Biol Reprod 2002;31:365-70.
- Sandhu S1, Arafat O, Patel H, Lall C. Krukenberg Tumor: a Rare cause of Ovarian Torsion. Journal of Clinical Imaging Science, 2012 Vol. 2, Issue 1.
- Hyun Kwon Ha, Seung Von Baek, Seung Hyup Kim, Hak Hee Kim, Eun Chul Chung, Kyung Mo Yeon. Krukenberg’s Tumor of the Ovary: MR Imaging Features AJR 1995;164:1435-1439.
- Prat J. Ovarian carcinomas, including secondary tumors: diagnostically challenging areas. Mod Pathol 2005; 18: 99-111.
- Quiros RM, Desai DC. Multidisciplinary approach for the treatment of gastric cancer. Minerva Gastroenterol Dietol 2011; 57: 53-68.