Adnan YILDIRIM, Bilal ELBEY, Ümit KARAALP, Alparslan ŞAHİN, Ümit Can YAZGAN

Vernal keratokonjonktivitli olgularda ortalama trombosit hacmi ve nötrofil/lenfosit oranı

Amaç: Bu çalışmada vernal keratokonjonktiviti (VKK) olan hastaların nötrofil, eozinofil, lenfosit, trombosit sayısı, nötrofil/lenfosit oranı (NLO), ortalama trombosit hacmi (MPV) değerlendirilmesi amaçlanmıştır.Yöntemler: Bu çalışmada göz hastalıkları polikliniğine başvurmuş ve VKK tanısı almış olguların dosya kayıtları retrospektif olarak incelendi. Şaşılık dışında herhangi bir sistemik ve oküler hastalığı bulunmayan yaş ve cinsiyet uyumlu olgular kontrol grubuna dahil edildi. Tüm katılımcıların yaş ve cinsiyet verileri kaydedildi. Hemogram değerlerinden; MPV nötrofil, eozinofil, lenfosit, trombosit sayımı, NLO otomatik analizörlerle ölçüldü. Elde edilen veriler iki grup arasında karşılaştırıldı.Bulgular: Çalışma kapsamında 30 VKK ve 30 kontrol olgusu değerlendirildi. Gruplar arasında yaş ve cinsiyet açısından anlamlı farklılık saptanmadı. MPV ve NLO, VKK grubunda kontrol grubuna oranla daha yüksek olmasına rağmen istatistiksel olarak anlamlı değildi (sırasıyla p=0,19 ve p=0,16).Sonuç: Bu çalışmanın sonucunda MPV ve NLO değerlerinin VKK hastalığıyla ilişkili olmadığını gösterilmiştir. MPV ve NLO değerlerinin VKK'da istatistiksel olarak anlamlı olmamalarına rağmen daha yüksek olması VKK için yardımcı parametre olarak kullanılabilir

Mean platelet volume and neutrophil to lymphocyte ratio in patients with vernal keratoconjunctivitis

Objective: It was aimed to investigate the neutrophil, eosinophil, lymphocyte, platelet count, neutrophil to lymphocyte ratio (NLR) and mean platelet volume (MPV) in patients with vernal keratoconjunctivitis (VKC).Methods: The medical records of the VKC patients who admitted to ophthalmology polyclinic were evaluated. Age and sex matched control group was consisted with patients without any systemic or ocular disease except strabismus. Age and gender of all participants were recorded. Hemogram parameters such as mean platelet volume (MPV), neutrophil, eosinophil, lymphocyte, platelet count, NLR were measured by automatized analyzer. Data were compared between the groups.Results: Thirty patients and 30 control subjects were studied. There were no significant differences with respect to age and gender between groups. The mean MPV and NLR values were higher but not statistically significant in VKC group compared to control group (p=0.19, p=0.16, respectively). Conclusion: The results of the current study demonstrated that MPV and NLR values were not associated with VKC. Higher MPV and NLR results in patients with VKC although the differences were not reach statistically significances may suggest that MPV and NLR may be auxiliary parameter. J Clin Exp Invest 2015; 6 (1): 40-43

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