Erdem GÖKDENİZ, İmdat DİLEK, Cengiz DEMİR

The effects of iron deficiency anemia on the thyroid functions

Amaç: Bu çalışmanın amacı demir eksikliği anemisinin tiroid fonksiyonları üzerine etkisi ve demir tedavisi sonrası değişiklikleri belirlemektir.Gereç ve yöntem: Bu çalışma, 42 hasta ve 38 sağlıklı birey ile yapıldı. Demir eksikliği anemisi tanısı serum ferritin ve tam kan sayımı yapılarak kondu. Hasta grubunda tedavi öncesi ve iki aylık tedavi sonunda ve kontrol grubunda ise 12 saat açlıktan sonra kan örnekleri alınarak serbest triiyodotironin (ST3), serbest tiroksin (ST4), total triiyodotironin (TT3), total tiroksin (TT4), tiroid stimule edici hormon (TSH) ve kortizol değerleri çalışıldı.Bulgular: Hasta grubunda demir tedavisi öncesi, olguların %35.7’sinde sekonder ve %16.6’sında subklinik hipotiroidi bulundu. Hasta grubunda tedavi öncesi, TSH düzeyi kontrol grubuna göre anlamlı düzeyde yüksekti (p=0.001). ST3 düzeyleri hasta ve kontrol grupları arasında farklı değildi (p>0.05). Tedavi öncesi ST4 düzeyleri, kontrol grubuna göre, anlamlı düşüktü (p

Demir eksikliği anemisinin tiroid fonksiyonları üzerine etkisi

Objectives: The aim of the present study was to investigate the effect of iron deficiency anemia and iron treatment on the thyroid functions.Materials and methods: In this study, 42 patients and 38 healthy individuals were studied. Iron deficiency anemia was diagnosed by measurement of serum ferritin and complete blood counts. Free Triiodothyronine (FT3), free thyroxine (FT4), total triiodothyronine, total thyroxine, thyroid stimulating hormone (TSH) and cortisol levels were measured in blood samples before treatment and after two months of treatment with iron in patients group and after 12 hours of starvation in healthy controls.Results: Before iron treatment, secondary hypothyroidism (35.7%) and subclinical hypothyroidism (16.6%) were found in patient group. Before the treatment TSH levels in the patient group were higher than the control group (p=0.001). FT3 values were not different between patient and the control groups (p>0.05). Before the treatment FT4 levels were significantly lower than the control group (p

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