Tc-99m MIBI SPECT miyokard perfüzyon sintigrafisindeki revers redistribüsyon paterninin sol ventrikül ejeksiyon fraksiyonu üzerindeki etkisi

Amaç: Revers redistribüsyon paterni (RRP)'nin nedenleri ve prognostik önemi henüz netlik kazanmamıştır. Bu çalışmada amacımız; RRP'nin sol ventrikül ejeksiyon fraksiyonu (EF) üzerindeki etkisini değerlendirmektir.Yöntemler: Teknesyum-99m sestamibi miyokard perfüzyon sintigrafisi yapılmış ve normal olarak değerlendirilmiş hastaların görüntüleri retrospektif olarak incelendi. Tek gün protokolü ve/veya farmakolojik stres testi uygulanan hastalar çalışma dışı bırakıldı. RRP saptanan toplam 21 hasta çalışma kriterlerini sağladı. Bu hastaların tamamı RRP grubu olarak çalışmaya dahil edildi. Randomize seçilen 21 RRP saptanmayan hasta ise kontrol grubu olarak çalışmaya alındı. Transiyel iskemik dilatasyon (TID) skorları ve EF değerleri Quantitative Gated SPECT (QGS) programı kullanılarak otomatik olarak hesaplandı. Bulgular: Yaş, cinsiyet, hipertansiyon, aile hikayesi, hiperlipidemi ve diyabet yönünden RRP ve kontrol grubu arasında istatistiksel olarak anlamlı bir fark saptanmazken (p>0,05), sigara kullanımı yönünden anlamlı fark tespit edildi (p=0,019). RRP grubundaki TID skorları, kontrol grubuna kıyasla anlamlı bir şekilde daha düşüktü (p

Effect of the reverse redistribution pattern on the left ventricular ejection fraction in the Tc- 99m MIBI SPECT myocardial perfusion scintigraphy

Objective: The causes and prognostic significance of the reverse redistribution pattern (RRP) is not clear yet. In this study, we aimed to evaluate the RRP effect on the left ventricular ejection fraction (EF).Methods: Imaging of the patients whose technetium-99m sestamibi myocardial perfusion scintigraphy was carried out and reported as normal were retrospectively examined. One-day protocol and/or pharmacologic stress testing applied patients were excluded. 21 patients with RRP met the inclusion criteria. All of these patients were included in the study as RRP group. Randomly selected 21 patients with non-RRP were included in the study as control group. Transient ischemic dilation (TID) scores and EF values were automatically calculated with the Quantitative Gated SPECT (QGS) program. Results: While a statistically significant difference was not found between the RRP and control groups in terms of age, sex, hypertension, family history, hyperlipidemia, and diabetes (p>0.05), there was a statistically significant difference in terms of smoking (p=0.019). TID scores in the RRP group were significantly lower compared to the control group (p

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Journal of Clinical and Experimental Investigations-Cover
  • Başlangıç: 2010
  • Yayıncı: Sağlık Araştırmaları Derneği
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