Şule KARAKELLEOĞLU, Hüseyin ŞENOCAK, Zuhal ARITÜRK, Habib ÇİL, Ebru TEKBAŞ ÖNTÜRK, Mehmet Ali ELBEY, Şakir ARSLAN, Enbiya AKSAKAL

Relationship between the severity of mitral regurgitation, left ventricular dysfunction and plasma brain natriuretic peptide level: An observational strain imaging study

Amaç: Bu çalışmada mitral yetersizliği ve strain/strain rate (S/SR) ekokardiyografi ile tespit edilen sol ventrikül disfonksiyonunun derecesi ile plazma beyin natriüretik peptid seviyesi arasındaki ilişkinin araştırılması amaçlanmıştır. Gereç ve yöntem: Mevcut çalışma kesitsel, gözlemsel bir çalışmadır. Bu çalışmaya polikliniğimize başvurmuş olan ardışık 31 mitral yetersizliği hastası (15’i [%48,4] erkek) ve kontrol grubu olarak 25 sağlıklı birey (12’si [%48,0] erkek) alınmıştır. Hastalar orta derecede mitral yetmezliği olanlar (n=14 [%45,2] ve ileri derecede mitral yetmezliği olanlar (n=17 [%54,8] olarak iki gruba ayrılmışlar ve üç grupta sol ventrikül duvar segmentlerinin maksimum strain / strain rate ölçümleri kaydedilmiş, plazma beyin natriüretik peptit seviyeleri ölçülmüştür. Bulgular: İleri MY olan hastalarda orta MY ve kontrol grubu ile karşılaştırıldığında ileri MY grubunda sol ventrikül segment S/SR değerlerinde daha belirgin azalma izlendi (p

Mitral yetersizliği şiddeti, sol ventrikül fonksiyon bozukluğu ve plazma beyin natriüretik peptit düzeyi arasındaki ilişki: Bir gözlemsel strain görüntüleme çalışması

Objectives: The aim of the this study was to investigatethe relationship between the degree of mitral regurgitation (MR), left ventricular (LV) dysfunction determined bystrain (S)/strain rate (SR) imaging and plasma brain natriuretic peptide (BNP) levels.Materials and methods: This is an observational cross- sectional study which included 31 consecutive patients (15[48.4%] male) who had applied to our outpatient clin- ics and diagnosed as mitral regurgitation and 25 (12 [48.0%] male) healthy persons as control subjects. The mitral regurgitation patients were divided into two groups: those with moderate MR (n=14[45.2%]) and those with severe MR (n=17[54.8%]), and maximum strain / strain rate measurements of left ventricular wall segments and plasma brain natriuretic peptide levels were determined in these two groups and controls. Results: S/SR values of all wall segments of left ventricle were found to be decreased in patient with severe MR when compared with the control subjects and patients with moderate MR (p

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