Yahya İSLAMOĞLU, Habib ÇİL, Zuhal ATILGAN ARITÜRK, Ahmet ÇALIŞKAN, Celal YAVUZ, Mustafa OYLUMLU, Sinan DEMİRTAŞ

Nötrofil/lenfosit oranı ile koroner kollateral dolaşım arasındaki ilişki

Amaç: Koroner kollateral dolaşım ile nötrofil/lenfosit oranı arasındaki ilişkiyi araştırmak. Gereç ve yöntem: Çalışmaya Dicle Üniversitesi Tıp Fakültesi Kardiyoloji kliniğine koroner arter hastalığı (akut koroner sendrom veya stabil angina pektoris) ön tanısıyla başvurup koroner anjiyografide en az bir damarında %70 den fazla darlık saptanan hastalar alındı. Tüm hastaların yaş, cinsiyet, diyabet ve hipertansiyonu varlığı, akut/stabil koroner sendrom varlığı, vücut kitle indeksi, nötrofil/lenfosit oranı, beyaz küre sayısı, Rentrop skoru, hastalıklı damar sayısı kaydedildi. Çalışmaya toplam 82 hasta alındı. Bulgular: Çalışmaya alınan hastalardan 33’ünde iyi gelişmiş kollateral dolaşım saptanırken 49’unda zayıf kollateral dolaşım saptandı. İki gurubun klinik özellikler yaş, cinsiyet, vücut kitle indeksi, hipertansiyon ve diyabet varlığı açısından benzer bulundu. İyi gelişmiş koroner kollateral dolaşım gurubunda ortalama NLO 2,78 iken zayıf kollateral dolaşım gurubunda 2,89 olarak saptandı. Ancak aradaki fark istatistiksel olarak anlamlı bulunmadı (p=0.12). Sonuç: Elde ettiğimiz verilerle nötrofil/lenfosit oranı ile iyi gelişmiş kollateral dolaşım arasında ilişki saptanmadı.

Association between neutrophil/lymphocyte ratio and coronary collateral circulation

Objectives: To investigate relation between neutrophil/ lymphocyte ratio and coronary collateral flow. Material and methods: Eighty-two patients admitted Dicle University Medical Faculty Hospital Cardiology Department with diagnosis of coronary artery disease and detected significant stenosis or occlusion at least one of the coronary arteries, were included to study. Age, sex, presence of diabetes mellitus and hypertension, acute/ stable coronary disease, body mass index, neutrophil/ lymphocyte ratio, white blood count, Rentrop scores and number of diseased vessel were recorded. Results: Well-developed coronary collateral circulation was found in 33 of the patients. Forty-nine patients had poor coronary collateral circulation. Mean age, sex, body mass index, presence of diabetes mellitus and hypertension were similar in two groups. Mean neutrophil/lymphocyte ratio was lower in well-developed coronary collateral circulation group than poor coronary collateral circulation group, but there was no significant differences (2.78 vs 2.89, p=0.12). Conclusions: There was no association between neutron/ hil lymphocyte ratio and coronary collateral circulation according to our data. J Clin Exp Invest 2012; 3(1): 29-32

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