Yasemin TOPCU, Erhan BAYRAM, Ertan KAYSERİLİ, Semra HIZ, Meral BAYRAM TORUN

Long term neurodevelopmental outcome of preterm infants with periventricularintraventricular hemorrhage

Amaç: Periventriküler-intraventriküler kanaması bulunan prematüre bebeklerin, 4 yaş, nörogelişimsel morbiditelerinin belirlenmesi. Gereç ve yöntem: Dört yaşındaki hastalar, nörolojik muayene ve motor değerlendirmeleri için bir çocuk nöroloğu tarafından ve Denver II Gelişimsel Tarama Testleri için bir psikolog tarafından değerlendirildi. Sonuçlar, 3-6 ay ve 6-12. ayda yapılan Denver II Gelişimsel Tarama Testleri sonuçları ile karşılaştırıldı. Bulgular: Evre III-IV periventriküler-intraventriküler kanaması bulunan olguların 4 yaşındaki Denver II Gelişimsel Tarama Testleri, evre I-II periventriküler-intraventriküler kanaması bulunan grupla karşılaştırıldığında belirgin olarak geri idi. Aynı şekilde, ≤ 32 hafta doğan olgular > 32 hafta doğanlarla karşılaştırıldığında, 4 yaşındaki Denver II Gelişimsel Tarama Testleri belirgin olarak geri saptandı. Sonuç: Sonuç olarak, ≤ 32 gestasyonel haftada doğan ve/veya evre III-IV periventriküler-intraventriküler kanaması olan olgularda nörolojik etkilenme riski artmaktadır. Bütün prematüre bebkler, erken çocukluk döneminde Denver II Gelişimsel Tarama Testi ile değerlendirilmelidir.

Periventriküler-intraventriküler kanaması bulunan prematür bebeklerin uzun dönem nörogelişimsel sonuçları

Objectives: To determine the neurodevelopmental morbidity of preterm infants with periventricular- intraventricular hemorrhage, at the age of 4. Materials and methods: The patients at the age of 4 were evaluated through neurologic examination and motor assessment by a pediatric neurologist and Denver II Developmental Screening Test by a psychologist. The results were compared with Denver II Developmental Screening Test results which had been made at 3-6 and 6-12 months. Results: Patients with grade ІІІ-ІV Periventricular-Intraventricular Hemorrhage had significantly lower Denver II Developmental Screening Test results at the age of 4, compared with grade І-ІІ Periventricular-Intraventricular Hemorrhage group. Similarly, ≤ 32 weeks patients had significantly lower Denver II Developmental Screening Test at the age of 4 when compared with > 32 weeks patients. Conclusions: Children who were born ≤ 32 gestational weeks and/or patients with grade ІІІ-ІV periventricularintraventricular Hemorrhage have an increased risk of neurologic impairment. All premature infants should be evaluated by Denver II Developmental Screening Test in early childhood period of life.

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