Ameenah GURIB-FAKIM, Anwar Hussein UBRATTY, Fawzia Bibi NAROD

Biological investigations into Antidesma madagascariense Lam. (Euphorbiaceae), Faujasiopsis flexuosa (Lam.) C. Jeffrey (Asteraceae), Toddalia asiatica (L.) LAm. and vepris lanceolata (Lam.) G. Don (Rutaceae)

Mauritus'un endemik tıbbi bitkileri olan Antidesma madagascariense Lam. (Euphorbiaceae), Faujasiopsis flexuosa (Lam.) C. Jeffrey (Asteraceae), Toddalia asiatica (L.) Lam. and Vepris lanceolata (Lam.) G. Don (Rutaceae) dan elde edilen ekstreler antimikrobiyal aktivitelerini belirlemek üzere tarandı. Sonuçlara göre denenen 28 ekstreden 20 sinin denenen dört bakteriden en az birine karşı antibakteriyel aktivite gösterdiği, diğer taraftan 17 ekstrenin denenen iki mantardan en az birine karşı antifungal aktivite gösterdiği saptandı. Ayrıca bu bitkilerden elde edilen sekiz ekstrenin, in vitro da izole edilen sıçan düz kaslarında kasılmaya sebep olduğu belirlendi. Ayrıca geleneksel yöntemlerle tedavi yapanların reçetelerine yazmaları için üç bitki çayının yürürlüğe girmesi girişiminde bulunuldu.

Antidesma madagascariense lam. (Euphorbiaceae), Faujasiopsis flexuosa (Lam.) C. Jeffrey (Asteraceae), Toddalia asiatica (L.) Lam. and Vepris lanceolata (Lam.) G. Don (Rutaceae) da biyolojik araştırmalar

Extracts obtained from four endemic medicinal plants of Mauritius, namely, Antidesma madagascariense Lam. (Euphorbiaceae), Faujasiopsis flexuosa (Lam.) C. Jeffrey (Asteraceae), Toddalia asiatica (L.) Lam. and Vepris lanceolata (Lam.) G. Don (Rutaceae), were screened for antimicrobial activity. Our results showed that twenty out of twenty-eight tested extracts possessed antibacterial activity against at least one of the four test bacteria, while 17 extracts showed antifungal activity against at least one of the two test fungi. Furthermore, eight extracts obtained from these plants were found to elicit contractile responses in isolated rat smooth muscles in-vitro. Attempts were also made towards the validation of three herbal teas prescribed by traditional healers.

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