UTERUS TRANSPLANTASYONUNDA CANLI VE ÖLÜ DONÖR SEÇİMİ

Doğurganlık çağındaki her 500 kadından birinde uterin faktör infertilitesi bulunmaktadır. Uterin faktör infertilitesine neden olan durumlar arasında; endometrial ve servikal kanser nedeniyle histerektomi, müllerian kanal agenezisi nedeniyle uterus ve vajina gelişiminin olmaması, uterus unikornus, bikornus ve uterin septum nedeniyle implantasyon başarısızlığı ve abortus, şiddetli uterin adhezyonlar yer almaktadır. Uterus transplantasyonu, uterin faktörü infertilitesi olan kadınların gebe kalabilmelerine ve bebeklerini taşıyabilmelerine imkân sunmaktadır. Ayrıca, transplante edilen uterusun alıcıda geçici bir süreliğine kalması nedeniyle uzun dönemde görülebilecek immünolojik ret reaksiyonu riski de önemli ölçüde azalmaktadır. Şu ana kadar canlı donörden nakledilen uterusla dokuz canlı doğum, ölü donörden nakledilen uterusla da bir canlı doğum bildirilmiştir. Transplantasyon için hem canlı hem de ölü donör kullanımına yönelik başarılı örneklerin olması bu yöntemin gelişimi için umut vericidir.

Anahtar Kelimeler:

Canlı donör, ölü donör, uterus transplantasyonu

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