Saeed NAZIFI, Fatemeh ABBASI, Javad TAJIK

KARACİĞER APSELİ SIĞIRLARDA SERUM PROTEİNLERİNİN DEĞERLENDİRİLMESİ

Araştırmada, karaciğer apseleri bulunan ineklerin serum protein elektroforezinin ve serum proteinlerindeki değişimlerin korelasyonlarının değerlendirilmesi ve enfekte ineklerde karaciğerdeki enfeksiyon seviyesinin belirlenmesi amaçlarıyla kesimden sonra rastlantısal olarak seçilen 435 ineğin karaciğerleri incelenmiştir. İçlerinden 20 inekte karaciğer apsesi teşhis edilmiştir. Ölçülen karaciğer apselerinin çapları ile serum ?-globulin konsantrasyonları arasında oldukça önemli korelasyonlar (r=0,498, P=0,05) ve karaciğer apselerinin çapları ile serum total protein (r=0,487, P=0,056) ve total globulin (r=0,438, P=0,09) arasında ise daha düşük öneme sahip korelasyonlar bulunmuştur. Ayrıca, karaciğerde bulunan apse sayıları ile serum ?- globulin konsantrasyonu (r=0,506, P=0,032) ve ?globulin oranları (r=0,463, P=0,05) arasında oldukça önemli korelasyonlar bulunmuştur. Bununla birlikte, karaciğerin sol lobunda apse bulunan ineklerin ?-globulin oranları, diyaframatik yüzeyde apse bulunan hayvanlara göre daha yüksek bulunmuştur (P=0,013). Karaciğerin tamamına ufak apseler olarak yayılan enfeksiyona sahip hayvanların ?globulin konsantrasyonları diyaframatik yüzeyde apse bulunan hayvanlara göre daha yüksek (P=0,036), karaciğerin sol kısmında apse bulunan hayvanların serum ?-globulin konsantrasyonlarına göre daha düşük bulunmuştur (P=0,07). Hayvanların yaşları ile ?-globulin oranları (r=-0,219, P=0,047) arasındaki önemli korelasyonlar ve hayvanların yaşları ile serum ?-globulin konsantrasyonları (r=-0,194, P=0,07) arasındaki daha düşük öneme sahip korelasyonlar ortaya konmuştur. Çalışmanın sonucunda, karaciğerinde apse bulunan ineklerin serum protein elektroforezi yardımı ile karaciğerdeki enfeksiyonun seviyesinin ve apselerin konumlarının belirlenebileceği ortaya konmuştur

Evaluation of Serum Proteins in Cattle with Liver Abscess

To evaluate the serum protein electrophoresis in cows with hepatic abscess and to investigate the correlation of changes in the serum proteins and the severity of hepatic involvement in affected cows, the liver of 435 randomly selected cattle were examined after slaughter. Liver abscesses were diagnosed in 20 cows. The size of hepatic abscesses (in diameter) had a significant correlation with serum concentration ?-globulin (r=0.498, P=0.05), and had marginally significant correlations with serum total protein (r=0.487, P=0.056) and total globulin (r=0.438, P=0.09). There were also significant correlations between the number of hepatic abscesses and serum concentration of ?-globulin (r=0.506, P=0.032) and ?-globulin percent (r=0.463, P=0.05). Also, cows with hepatic abscess on left lobe of the liver had a higher ?-globulin percent than the cows with hepatic abscess on diaphragmatic surface (P=0.013). Cows with diffused tiny hepatic abscesses had a significantly higher ?- globulin concentration than the cows with hepatic abscess on diaphragmatic surface (P=0.036), and a marginally significant less serum ?-globulin concentration in comparison to cows with hepatic abscess in left lobe of the liver (P=0.07). Age revealed a significant correlation with the ?-globulin percent (r=-0.219, P=0.047), and had a marginally significant correlation with the serum concentration of ?-globulin (r=-0.194, P=0.07). The results of the current study showed that the serum protein electrophoresis may be useful in evaluation of the severity of hepatic involvement and abscess location in cows suffering from hepatic abscess

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