Damızlık hindilerde kuluçka davranışlarının pimozid kullanılarak engellenmesi
Bu çalışmada, memelilerde analık içgüdülerini ortadan kaldıran dopamin antagonistlerinden Pimozid'in hindilerdeki kuluçka davranışlarını engellemede etkinliğinin ortaya konması amaçlanmıştır. Çalışmada derin kuluçkadaki 20 adet Amerikan Bronzu hindi kullanıldı. Kuluçka dönemindeki 10 adet hindiye 20 mg/kg dozda pimozid 20 mi serum fizyolojik içerisinde oral olarak 3 gün süreyle uygulanırken, diğer 10 hindiye ise uygulama grubu ile aynı zaman ve aynı hacimde serum fizyolojik (plasebo) verildi ve kontrol grubu oluşturuldu. Hindilerin kuluçka belirtileri olan yuvada yatma, gurklama, yumurtlama ve pelvis kemikleri arasındaki mesafeleri uygulama öncesi 3 gün, üç günlük uygulama süresi ve uygulamadan sonraki 3 gün boyunca kaydedildi. Çalışma sonucunda, pelvis kemikleri arasındaki mesafenin, uygulanan pimozid'nin etkisiyle tedavinin ikinci gününde önemli derecede arttığı gözlendi (p
Control of broody behaviors by pimozide in turkey hens
This study was planned to distinguish the presumptive effect of Pimozide, a dopamine antagonist which diminishes the maternal instincts in mammals. Twenty deeply broody American Bronze turkeys were used in the study. Ten of the turkeys were treated with 20 mg/kg pimozide in 20 ml of physiologic saline per os for 3 days, the other 10 have received a same volume of physiologic saline (placebo) for a same duration to be the control group. Staying in the nest, hissing, laying and pelvic bone distances of the turkeys were recorded during the first 3 days without treatment, during the 3 days of treatment and 3 days after the treatment. At the end of the study the pelvic bone distances of the treatment turkeys, have significantly increased at the first day of treatment (P
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