DÜZELTİCİ OSTEOTOMİ YAPILAN SEREBRAL PALSİ SEKELLİ ÇOCUKLARDA MORBİDİTEYİ ETKİLEYEN FAKTÖRLER

Amaç: Serebral palsi (SP), ilerleyici olmayan hasara bağlı hareket ve duruş bozuklukları ile karakterize nörogelişimsel bir hastalıktır. Femur varizasyon-derotasyon osteotomisi, SP’li hastalarda femoral anteversiyonu düzeltmek için yapılan cerrahi bir işlemdir. Bu çalışmanın amacı, düzeltici osteotomi uygulanan SP sekeli çocuklarda morbiditeyi etkileyen faktörleri belirlemektir.Gereç ve Yöntem: 2007-2020 yılları arasında SP sekeli olan ve düzeltme osteotomisi yapılan çocuklar çalışmaya dahil edildi. Hastalara ait bilgiler arşiv dosyalarından elde edildi ve retrospektif olarak değerlendirildi. 105 hasta perioperatif morbiditeye göre: Grup 1 (morbidite yok) 62 hasta ve grup 2 (morbidite var) 43 hasta olarak iki gruba ayrıldı.Bulgular: İki grup arasında yaş ve vücut kitle indeksi açısından anlamlı fark yoktu. ASA skorları Grup 2’de anlamlı olarak yüksek bulundu (p=0,006). Prognostik nutrisyonel indeks Grup 2’de anlamlı olarak daha düşüktü (p=0,001). Hastane yatış süresi ve yoğun bakım yatış süresi açısından anlamlı fark yoktu.Sonuç: Malnütrisyon, SP sekeli olan çocuk hastalarda postoperatif morbiditede artışa neden olan kritik bir faktördür. Varizasyon-derotasyon osteotomisi planlanan SP sekeli hastalarda postoperatif morbiditeyi azaltmak için hasta bazında tedavi planı hazırlanabilir.

FACTORS AFFECTING MORBIDITY IN CHILDREN WITH CEREBRAL PALSY SEQUELAE WHO UNDERWENT CORRECTIVE OSTEOTOMY

Objective: Cerebral palsy (CP) is a neurodevelopmental disease characterized by movement and posture disorders due to non-progressive damage. Femur varization-derotation osteotomy is a surgical procedure performed to correct femoral anteversion in patients with CP. The aim of this study is to determine the factors affecting morbidity in children with CP sequelae who underwent corrective osteotomy.Materials and Methods: Children with CP sequelae who underwent correction osteotomy were included in the study between 2007 and 2020. Information about the patients was obtained from the archived files and evaluated retrospectively. 105 patients were divided into two groups according to the perioperative morbidity: Group 1 (no morbidity) including 62 patients and group 2 (presence of morbidity) including 43 patients.Results: We did not report any significant differences between group 1 and 2 in terms of age and body mass index. In Group 2, ASA scores were higher significantly (p=0.006). Prognostic nutritional index was significantly lower in Group 2 (p=0.001). There was no significant difference in length of hospital and intensive care unit stay.Conclusion: Malnutrition is an important factor that causes an increase in postoperative morbidity in pediatric patients with CP sequelae. In patients with CP sequelae planned for varization-derotation osteotomy, a treatment plan can be prepared on a patient basis to reduce postoperative morbidity.

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  • 1. Patel DR, Neelakantan M, Pandher K, Merrick J. Cerebral palsy in children: a clinical overview. Transl Pediatr 2020;9:125-35. [CrossRef] google scholar
  • 2. Cantero MJP, Medinilla EEM, Martinez AC, Gutierrez SG. Comprehensive approach to children with cerebral palsy. An Pediatr (Engl Ed) 2021;95(4):276.e1-276.e11. [CrossRef] google scholar
  • 3. Miller B, Rondeau B. Anesthetic considerations in patients with cerebral palsy. [Updated 2021 Nov 3]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2022. Available from: https://www.ncbi.nlm.nih.gov/books/ NBK572057/ google scholar
  • 4. Karslıoğlu B, Tekin AC, Tasatan E, Erkin FM. Hip disorders in cerebral palsy patients: diagnostic and therapeutic approaches. Eur Res J 2018;4(4):405-10. [CrossRef] google scholar
  • 5. Sung KH, Kwon SS, Chung CY, Lee KM, Cho GH, Park MS. Long-term outcomes over 10 years after femoral derotation osteotomy in ambulatory children with cerebral palsy. Gait Posture 2018;64:119-25. [CrossRef] google scholar
  • 6. Bendon AA, George KA, Patel D. Perioperative complications and outcomes in children with cerebral palsy undergoing scoliosis surgery. Paediatr Anaesth 2016;26(10):970-5. [CrossRef] google scholar
  • 7. Figueroa MJ, Rojas C, Barja S. Morbimortality associated to nutritional status and feeding path in children with cerebral palsy. Rev Chil Pediatr 2017;88:478-86. [CrossRef] google scholar
  • 8. Eminovic S, Vincze G, Eglseer D, Riedl R, Sadoghi P, Leithner A, et al. Malnutrition as predictor of poor outcome after total hip arthroplasty. Int Orthop (SICOT) 2021;45(1):51-6. [CrossRef] google scholar
  • 9. Adiamah A, Skorepa P, Weimann, Arved W, Lobo DN. The Impact of Preoperative Immune Modulating Nutrition on Outcomes in Patients Undergoing Surgery for Gastrointestinal Cancer:A Systematic Review and Meta-analysis. Ann Surg 2019;270(2):247-56. [CrossRef] google scholar
  • 10. Ohwada H, Nakayama T, Kanaya Y, Tanaka Y. Serum albumin levels and their correlates among individuals with motor disorders at five institutions in Japan. Nutr Res Pract 2017;11(1):57-63. [CrossRef] google scholar
  • 11. Liu Q, Gao K, Zheng C, Guo C. The Risk Factors for Perioperative Serum Albumin Variation in Pediatric Patients Undergoing Major Gastroenterology Surgery. Front Surg 2021;7:627174. [CrossRef] google scholar
  • 12. Yu J, Hong JP, Suh HP, Park JY, Kim DH, Ha S, et al. Prognostic Nutritional Index is a Predictor of Free Flap Failure in Extremity Reconstruction. Nutrients 2020;12(2):562. [CrossRef] google scholar
  • 13. Jeon HG, Choi DK, Sung HH, Jeong BC, Seo SI, Jeon SS, et al. Preoperative Prognostic Nutritional Index is a Significant Predictor of Survival in Renal Cell Carcinoma Patients Undergoing Nephrectomy. Ann Surg Oncol 2016;23(1):321-7. [CrossRef] google scholar
  • 14. Mohri Y, Inoue Y, Tanaka K, Hiro J, Uchida K, Kusunoki M. Prognostic Nutritional Index Predicts Postoperative Outcome in Colorectal Cancer. World J Surg 2013;37(11):2688-92. [CrossRef] google scholar
  • 15. Cadwell JB, Afonso AM, Shahrokni A. Prognostic nutritional index (PNI), independent of frailty is associated with six-month postoperative mortality. J Geriatr Oncol 2020;11(5):880-4. [CrossRef] google scholar
  • 16. Reece L, Dragicevich H, Lewis C, Rothwell C, Fisher OM, Carey S, et al. Preoperative Nutrition Status and Postoperative Outcomes in Patients Undergoing Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy. Ann Surg Oncol 2019;26(8):2622-30. [CrossRef] google scholar
  • 17. Obana KK, Fan BB, Bennett JT, Lin A, Goldstein RY, Andras LM, et al. Pre-operative nutrition assessments do not improve outcomes in cerebral palsy patients undergoing varus derotational osteotomy. Medicine 2021;100(47):e27776. [CrossRef] google scholar
  • 18. Lee SY, Sohn HM, Chung CY, Do SH, Lee KM, Kwon SS, et al. Perioperative Complications of Orthopedic Surgery for Lower Extremity in Patients with Cerebral Palsy. J Korean Med Sci 2015;30(4):489-94. [CrossRef] google scholar
  • 19. Nazareth A, Shymon SJ, Andras L, Goldstein RY, Kay RM. Impact of tranexamic acid use on blood loss and transfusion rates following femoral varus derotational osteotomy in children with cerebral palsy. J Child Orthop 2019;13(2):190-5. [CrossRef] google scholar
  • 20. Inan M, Senaran H, Domzalski M, Littleton A, Dabney K, Miller F. Unilateral Versus Bilateral Peri-ilial Pelvic Osteotomies Combined With Proximal Femoral Osteotomies in Children With Cerebral Palsy: Perioperative Complications. J Pediatr Orthop 2006;26(4):547-50. [CrossRef] google scholar
İstanbul Tıp Fakültesi Dergisi-Cover
  • Başlangıç: 1916
  • Yayıncı: İstanbul Üniversitesi Yayınevi
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