Mahmut ASLAN, Serkan KIRIK, Serdal GÜNGÖR

ÇOCUKLUK ÇAĞINDAKİ OPTİK NÖRİT TANILI HASTALARIN DEĞERLENDİRİLMESİ

Amaç: Optik nörit (ON), akut ve subakut görme kaybı ile başlayan, optik sinirin demiyelinizasyonu ile karakterize bir otoimmün hastalıktır. İzole, idiyopatik bir durum olarak ortaya çıkabildiği gibi Multipl Skleroz (MS) veya Nöromiyelitis Optika (NMO) gibi hastalıkların öncüsü de olabilir. Çalışmamızda çocuk hastalarda optik nörit tanılı vakaların demografik özelliklerini ve uzun dönem prognozu değerlendirmeyi amaçladık. Gereç ve Yöntem: Bu çalışmada, 2010-2017 yılları arasında çocuk nöroloji kliniğine başvuran ve akut ON tanısı alan hastalar retrospektif olarak değerlendirildi. Bulgular: ON tanısı alan 13 hasta çalışmaya dahil edildi. Bunların 6’sına (%46,15) izole ON tanısı kondu. Hastaların dokuzu kadın ve ortalama yaş 12,8±3,07 yıldı. Yedi hastada (%53,85) tek taraflı tutulum vardı. On iki hastada tam bir iyileşme sağlanırken, MS tanısı alan iki hastanın takibinde nüks gelişti. Sonuç: Görme bulanıklığı ve görme kaybı olan her çocukta ON mutlaka düşünülmelidir. Erken dönem steroid tedavisi en etkili tedavidir.

Anahtar Kelimeler:

Demiyelinizan hastalık, optik nörit, pediatrik

AN EVALUATION OF PATIENTS DIAGNOSED WITH OPTIC NEURITIS IN CHILDHOOD

Objective: Optic neuritis (ON) is an autoimmune disease that starts with acute and subacute vision loss and is characterized by the demyelination of the optic nerve. It may appear as an isolated, idiopathic condition, or it may be a precursor of diseases such as Multiple Sclerosis (MS) or Neuromyelitis Optica (NMO). In the study, we aimed to evaluate ON patients and the longterm prognosis in pediatric patients. Material and Method: In this study, 13 patients who applied to the pediatric neurology clinic between years 2010-2017 and were diagnosed with acute ON were assessed retrospectively. Results: Thirteen patients diagnosed with ON were included in our study, six of whom were diagnosed with isolated ON (6/13, 46.15%). Nine of them were female. The average age of our patients was 12.8±3.07 years. Seven patients (53.85%) had unilateral involvement. A complete recovery was provided in 12 patients. There were recurrences in the follow-up of two patients, diagnosed with MS. Conclusion: ON should absolutely be considered in every child with blurred vision and vision loss. Early stage steroid treatment is the most efficient therapy.

Keywords:

Demyelinating disease, optic neuritis, pediatric,

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