Medicinal values of a horticultural plant - Coleus hadiensis (Forssk.) A. J. Paton

Medicinal values of a horticultural plant - Coleus hadiensis (Forssk.) A. J. Paton

Coleus hadiensis (Forssk.) A.J.Paton is a horticultural herb that goes to the Lamiaceae family. This plant species has been using to treat diarrhea, skin and digestive disorders, diabetes, and carcinoma in ethnomedicines. This minireview work purposes to analyze, summarize, and document the reported bioactivities of C. hadiensis. Suitable published works were obtained employing the Web of Science, Scopus, PubMed, Semantic Scholar, and ScienceDirect databases from 1900 to December 2020. Hitherto, in vitro level of scientific evidence is the highest level of scientific evidence available for the bioactivities of this plant species. Various parts of C. hadiensis exhibited antioxidant, antibacterial, anti-inflammatory, anticancer, and antimalarial activities in a range of assays. To date, eight bioactive (antimalarial and antioxidant) compounds have been isolated from C. hadiensis. This minireview analyzed, summarized, and documented the reported bioactivities of C. hadiensis. In addition, this minireview provides a basis for further bioactivities researches using C. hadiensis in future.

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  • Ji, H. S, H., Li, Eun-Jin M., Un-Hee K., Young-ho K., Ho-Yong P., Tae-Sook J. 2019. Low-Density Lipoprotein-Antioxidant Flavonoids and a Phenolic Ester from Plectranthus hadiensis var. tomentosus. Applied Biological Chemistry, 62(1): 58.
  • Kew Science. 2020. Coleus hadiensis (Forssk.) A.J.Paton. Plants of the World Online. 2020. http://plantsoftheworldonline.org/taxon/urn:lsid:ipni.org:names:77201104-1.
  • Lukhoba, C.W., M.S.J. Simmonds, Paton, A.J. 2006. Plectranthus: A Review of Ethnobotanical Uses. Journal of Ethnopharmacology 103 (1): 1–24.
  • Menon, D.B., Sasikumar, J. M., Latha, K. 2012. Phytochemical Analysis and Antioxidant Activity of Methanolic Extract of Plectranthus hadiensis (Forssk.) Schweinf. Ex Spreng. Aerial Parts. Indian Journal of Natural Products and Resources 3 (3): 359–65.
  • Menon, D.B., Gopalakrishnan, V.K. 2015. Terpenoids Isolated from the Shoot of Plectranthus hadiensis Induces Apoptosis in Human Colon Cancer Cells via the Mitochondria-Dependent Pathway. Nutrition and Cancer 67 (4): 697–705.
  • Menon, D.B., J.M. Sasikumar, and V.K. Gopalakrishnan. 2014. Antioxidant and Anti-Inflammatory Properties of Terpenoid Fraction Isolated from the Shoot of Plectranthus hadiensis. International Journal of Pharma and Bio Sciences 5 (2): B197–205.
  • Menon, D.B., Sasikumar, J.M., Latha, K. 2011. Anti-inflammatory and Cytotoxic Activity of Methanolic Extract of Plectranthus hadiensis Stem. Pharmacologyonline 3: 275–82.
  • Mothana, R.A.A., Abdo, S.A.A., Hasson, S., Althawab, F.M.N., Alaghbari, S.A.Z., Lindequist, U. et al. 2010. Antimicrobial, Antioxidant and Cytotoxic Activities and Phytochemical Screening of Some Yemeni Medicinal Plants. Evidence-Based Complementary and Alternative Medicine 7 (3): 323–30.
  • Rice, L. J., Brits, G. J., Potgieter, C. J., Staden, J.V. et al. 2011. Plectranthus: A Plant for the Future?” South African Journal of Botany, Special issue on Economic Botany, 77 (4): 947–59.
  • Rijo, P., Mariana B., Marisa M., Helga R., Sandra J., Miléa S. et al. 2018. Screening of Antioxidant and Antimicrobial Activities on Plectranthus Spp. Extracts: Pesquisa Das Actividades Antioxidante e Antimicrobiana Em Extractos de Plantas Do Género Plectranthus. Journal Biomedical and Biopharmaceutical Research 9 (2): 225–35.
  • Sathasivampillai, S.V., Rajamanoharan, P.R., Munday, M., Heinrich, M. et al. 2018. Siddha Medicine in Eastern Sri Lanka Today–Continuity and Change in the Treatment of Diabetes. Frontiers in Pharmacology 9.
  • Sathasivampillai, S.V., Rajamanoharan, P.R., Munday, M., Heinrich, M. et al. 2017. Plants Used to Treat Diabetes in Sri Lankan Siddha Medicine – An Ethnopharmacological Review of Historical and Modern Sources. Journal of Ethnopharmacology 198 (February): 531–99.
  • Sathasivampillai, S.V., Rajamanoharan, P.R., Munday, M., Heinrich, M. et al. 2015. Preparations and Plants Used to Treat Diabetes in Sri Lankan Siddha Medicine. In: Colombo: Institute of Indigenous Medicine, University of Colombo.
  • Sripathi, R., Dharani J., Subban R. 2018. A Study on the Seasonal Variation of the Essential Oil Composition from Plectranthus hadiensis and Its Antibacterial Activity. Natural Product Research 32 (7): 871–74.
  • Sripathi, R., Subban R. 2017. Chemical Composition and Antibacterial Activity of the Essential Oil from the Seeds of Plectranthus Hadiensis. International Journal of Pharmacognosy and Phytochemical Research 9 (5): 637–39.
  • Van Zyl, R.L., Khan, F., Edwards, T.J., Drewes, S.E. 2008. Antiplasmodial Activities of Some Abietane Diterpenes from the Leaves of Five Plectranthus Species. South African Journal of Science 104 (1–2): 62–64.