Ester MOULİN, ítalo WERNER, Jaqueline SOUZA, Milene FONTES, Janaína VİLLANOVA, Tercio SOUZA

Extraction, characterization, and evaluation of the functionality of fixed oil low-quality coffee beans for use as pharmaceutical ingredients

In order to offer a viable destination for green coffee beans classified as non-beverage type, this work aimed to extract and characterize the fixed oil from these beans and perform a preliminary evaluation of its functionality as a pharmaceutical ingredient. The extraction yield obtained was 3.70 ± 1.29% (w/w). The oil present in its composition high levels of fatty acids with emulsifying and emollient properties, palmitic acid (47.76%) and linoleic acid (32.98%); and compounds with antioxidant functional properties, tocopherols (788.71 ± 56.08 mg/kg) and phenolic compounds (3312.40 ± 14.62 mg/kg). This oil showed antioxidant activity against the free radical 2,2-diphenyl-1-picryl hydrazil at all tested concentrations, reaching 50% inhibition at the concentration of 0.59 mg/ml and 90% at 0.96 mg/ml. The preliminary evaluation of the physical stability of the creams showed that, when incorporated into formulations, this oil has the potential to be used as a substitute for the synthetic ingredients liquid petrolatum, decyl oleate, and butylated hydroxytoluene.

Keywords:

Natural antioxidant, Pharmaceutical emulsions, Cosmetics, Green coffee,

Tam Metin

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Bibtex	@araştırma makalesi { ijpbp1037204, journal = {International Journal of Plant Based Pharmaceuticals}, eissn = {2791-7509}, address = {Kilis 7 Aralık Üniversitesi, Fen-Edebiyat Fakültesi, Moleküler Biyoloji ve Genetik Bölümü, 79000, Merkez-KİLİS}, publisher = {Kilis 7 Aralık Üniversitesi}, year = {2022}, volume = {2}, number = {2}, pages = {155 - 165}, title = {Extraction, characterization, and evaluation of the functionality of fixed oil low-quality coffee beans for use as pharmaceutical ingredients}, key = {cite}, author = {Moulin, Ester and Werner, ítalo and Souza, Jaqueline and Fontes, Milene and Villanova, Janaína and Souza, Tercio} }
APA	Moulin, E. , Werner, í. , Souza, J. , Fontes, M. , Villanova, J. & Souza, T. (2022). Extraction, characterization, and evaluation of the functionality of fixed oil low-quality coffee beans for use as pharmaceutical ingredients . International Journal of Plant Based Pharmaceuticals , 2 (2) , 155-165 .
MLA	Moulin, E. , Werner, í. , Souza, J. , Fontes, M. , Villanova, J. , Souza, T. "Extraction, characterization, and evaluation of the functionality of fixed oil low-quality coffee beans for use as pharmaceutical ingredients" . International Journal of Plant Based Pharmaceuticals 2 (2022 ): 155-165 <
Chicago	Moulin, E. , Werner, í. , Souza, J. , Fontes, M. , Villanova, J. , Souza, T. "Extraction, characterization, and evaluation of the functionality of fixed oil low-quality coffee beans for use as pharmaceutical ingredients". International Journal of Plant Based Pharmaceuticals 2 (2022 ): 155-165
RIS	TY - JOUR T1 - Extraction, characterization, and evaluation of the functionality of fixed oil low-quality coffee beans for use as pharmaceutical ingredients AU - EsterMoulin, ítaloWerner, JaquelineSouza, MileneFontes, JanaínaVillanova, TercioSouza Y1 - 2022 PY - 2022 N1 - DO - T2 - International Journal of Plant Based Pharmaceuticals JF - Journal JO - JOR SP - 155 EP - 165 VL - 2 IS - 2 SN - -2791-7509 M3 - UR - Y2 - 2022 ER -
EndNote	%0 International Journal of Plant Based Pharmaceuticals Extraction, characterization, and evaluation of the functionality of fixed oil low-quality coffee beans for use as pharmaceutical ingredients %A Ester Moulin , ítalo Werner , Jaqueline Souza , Milene Fontes , Janaína Villanova , Tercio Souza %T Extraction, characterization, and evaluation of the functionality of fixed oil low-quality coffee beans for use as pharmaceutical ingredients %D 2022 %J International Journal of Plant Based Pharmaceuticals %P -2791-7509 %V 2 %N 2 %R %U
ISNAD	Moulin, Ester , Werner, ítalo , Souza, Jaqueline , Fontes, Milene , Villanova, Janaína , Souza, Tercio . "Extraction, characterization, and evaluation of the functionality of fixed oil low-quality coffee beans for use as pharmaceutical ingredients". International Journal of Plant Based Pharmaceuticals 2 / 2 (Aralık 2022): 155-165 .
AMA	Moulin E. , Werner í. , Souza J. , Fontes M. , Villanova J. , Souza T. Extraction, characterization, and evaluation of the functionality of fixed oil low-quality coffee beans for use as pharmaceutical ingredients. Int. J. Plant Bas. Pharm.. 2022; 2(2): 155-165.
Vancouver	Moulin E. , Werner í. , Souza J. , Fontes M. , Villanova J. , Souza T. Extraction, characterization, and evaluation of the functionality of fixed oil low-quality coffee beans for use as pharmaceutical ingredients. International Journal of Plant Based Pharmaceuticals. 2022; 2(2): 155-165.
IEEE	E. Moulin , í. Werner , J. Souza , M. Fontes , J. Villanova ve T. Souza , "Extraction, characterization, and evaluation of the functionality of fixed oil low-quality coffee beans for use as pharmaceutical ingredients", , c. 2, sayı. 2, ss. 155-165, Ara. 2022