Pseudevernia furfuracea (L.) Zopf Liken Türünün Antibakteriyel Aktivitesi Ve Antioksidan Kapasitesinin Araştırılması

Bir mantar (mikobiyont) ve bir yeşil algin ve/veya siyanobakterinin (fotobiyont) bir araya gelmesiyle oluşan likenler; bu ortak yaşam sonucunda kendilerine özgü sekonder metabolitler üretirler. Yapılan araştırmalarda likenlerin bu sekonder metabolitler sayesinde çeşitli biyolojik aktivitelere ve antibakteriyel etkilere sahip oldukları bildirilmektedir. Bu çalışmada dalsı liken Pseudevernia furfuracea (L.) Zopf türüne ait örneklerden elde edilen aseton ekstrelerinin ATCC 29212 Enterococcus faecalis, ATCC 25923 Staphylococcus aureus, CECT 4122 Pseudomonas aeruginosa, ATCC 25922 Escherichia coli suşları üzerindeki antibakteriyel aktiviteleri disk difüzyon yöntemi ile araştırılmıştır. Ayrıca aynı liken ekstrelerinin antioksidan kapasiteleri CUPRAC metodu kullanılarak değerlendirilmiştir. Elde edilen sonuçlara göre, P. furfuracea aseton ekstreleri Gram negatif bakterilere karşı etkisiz olurken Gram pozitif bakterilerin gelişimini inhibe etmiştir. Antioksidan olarak ise 9,653 ± 0,102 µg TE/gr değerinde hesaplanan iyi düzeyde aktivite göstermiştir. P. furfuracea liken türünün farmakoloji alanında doğal kaynak olarak kullanılabileceği öngörülmektedir.

Anahtar Kelimeler:

liken, Pseudevernia furfuracea, antibakteriyel aktivite, antioksidan kapasite, sekonder metabolit

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