OBSTRÜKTİF UYKU APNE SENDROMLU HASTALARDA GÜNDÜZ AŞIRI UYKULULUK HALİNİ ETKİLEYEN FAKTÖRLER

Bu çalışmanın amacı, obstrüktif uyku apne sendromu (OUAS) olan hastalarda aşırı gündüz uykululuk halini karakterize ederek klinik ve polisomnografik değişkenlerle ilişkisini belirlemektir. Apne hipopne indeksi 5 ve üzeri olan OUAS’lı hastalar (n = 143) çalışmaya dahil edilmiş olup, OUAS’lı hastalardan Epworth uykululuk ölçeği (EUÖ)≥ 10 olanlar gündüz aşırı uykululuğu pozitif kabul edilmiştir (n:73). EUÖ <10 olanlar gündüz aşırı uykululuğu negatif kabul edilmiştir. (n:70). EUÖ pozitif hastalar, EUÖ negatif hastalar ile karşılaştırıldığında; belirgin şekilde daha yüksek apne hipopne indeksi, gece daha düşük ortalama oksijen satürasyonu ve daha düşük ortalama desatürasyon indeksi gösterdi. EUÖ pozitif hastalarda solunumsal uyarılma indeksi ve ortalama apne süresi daha yüksek olduğu sonucuna ulaşılmıştır. OUAS’lılarda solunumsal uyarılma indeksi, apne hipopne indeksi, ortalama apne süresi ve gece oksijen satürasyonundaki düşmeler GAUH’ni belirlemede önemli rol oynayabilirler.

Anahtar Kelimeler:

Gündüz Aşırı Uykululuk Hali, Obtrüktif Uyku Apne Sendromu, Polisomnografi

FACTORS INFLUENCING EXCESSIVE DAYTIME SLEEPINESS in PATIENTS with OBSTRUCTIVE SLEEP APNEA SYNDROME

The aim of this study is to investigate the relationship between clinical and polysomnographic variables by characterizing excessive daytime sleepiness in patients with obstructive sleep apnea syndrome (OSAS). OSAS patients with apnea hypopnea index 5 and above (n = 143) are included in the study. Epworth Sleepiness Scale (EAP) ≥ 10 patients with OSAS are considered to be positive for daytime sleepiness (n: 73). Those with EEI <10 are considered negative in daytime excessive sleepiness (n: 70). When compared with the Epworth Sleepiness Scala (ESS) negative patients; significantly higher apnea hypopnea index, lower mean oxygen saturation at night, and lower mean desaturation index. Respiratory arousal index and mean apnea duration were higher in ESS positive patients. The respiratory arousal index, apnea hypopnea index, mean apnea duration and night oxygen saturation decrease in OSAS patients may play an important role in determining excessive-daytime sleepiness.

Keywords:

Excessive Daytime Sleepiness, Obstructive Sleep Apnea Syndrome, polysomnography,

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