Dosimetric fricke gel systems improved with CaCl2 and gluconic acid
Today, cancer is an increasingly important health problem that comes immediately after heart and vascular diseases as a cause of death. In this study primary objective is to generate an alternative to dosimetry systems that are not practical and cost effective due to increasingly complex external beam radiotherapy techniques. For this purpose, CaCl2 or Gluconic acid added dosimetric Fricke gel compounds were improved to mimic human tissues by means of interaction with X- rays. The MR intensity values were linearly changed depending on the concentrations of the produced gel samples and the dose amount of the applied radiation.
Keywords:
Dosimetric gels Fricke gels, Gluconic acid, CaCl2,
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- 1. Baldock, C., Historical overview of the development of gel dosimetry: another personal perspective. Journal of Physics: Conference Series, 2009. 164, 012002.
- 2. Gore, J.C., Kang, Y.S., Schulz, R.J., Measurement of radiation dose distributions by nuclear magnetic resonance (NMR) imaging. Phys. Med. Biol, Pub.Med., 1984. 29, 1189–1197.
- 3. Cardenasa, R.L., Cheng, K.H., Verhey, L.J., Xia, P., Davis, L., Cannon, B., A self consistent normalized calibration protocol for three dimensional magnetic resonance gel dosimetry. Magnetic Resonance Imaging, 2002. 20, 667–679.
- 4. Fricke, H., Morse, S.,The chemical action of Roentgen rays on dilute ferrous sulphate solutions as a measure of radiation dose. Am. J. Roentgenol. Radium Ther. Nucl. Med, 1927. 18, 430–432.
- 5. Balkwell, W.R. and Adams, G.D., On the radiation chemistry of the ferrous sulfate-benzoic acid dosimeter, Radiat. Res., 1960, 12, 419-420.
- 6. Hart, E.J., Mechanism of the ɤ-ray-induced chain oxidation of aqueous ferrous sulfate –formic acid - oxygen solutions, J. Am. Chem. Soc., 1952, 74,4174-4178.
- 7. Dewhurst, H.A., Effect of aliphatic alcohols on the ɤ-ray oxidation of aerated aqueous ferrous sulphate, Trans. Farad. Soc., 1952, 48, 905-911.
- 8. Ramachandran, S., Fontanille, P., Pandey, A. and Larroche,C.,Gluconic Acid: A Review, Food Technol. Biotechnol., 2006, 44(2) 185–195.
- 9. Gambarini, G., Arrigoni, S., Cantone, M.C., Molho, N., Facchielli L. and Sichirollo, A.E., Dose-response curve slope improvement and result reproducibility of ferrous-sulphate-doped gels analysed by NMR imaging. Physics in Medicine & Biology, 1994, 39(4), 703-717.
- 10. Hermanto, S., Sumarlin, L,O. and Fatimah, W., Differentiationof Bovine and Porcine GelatinBased on Spectroscopic and Electrophoretic Analysis, J.Food Pharm.Sci.2013, 1, 68-73.
- 11. Hossana, M.J., Gafurb, M.A., Kadirband, M.R. and Karim, M.M., Preparation and Characterization of Gelatin-Hydroxyapatite Composite for Bone Tissue Engineering, International Journal of Engineering & Technology IJET-IJENS, , 2014, 14(1), 24-32.
- 12. Gündüz, F. and Bayrak, B., Synthesis and performance of pomegranate peel-supported zero-valent iron nanoparticles for adsorption of malachite green, Desalination and Water Treatment, 2018, Acceoted, doi: 10.5004/dwt.2018.22185.
- Yayın Aralığı: Yılda 3 Sayı
- Başlangıç: 2017
- Yayıncı: Dr. Ceyhun YILMAZ